Skip to main content

Table 1 Clinical characteristics of pediatric untreated acute and IVIG-treated subacute and convalescent KD subjects and healthy and febrile controls

From: Differences in GlycA and lipoprotein particle parameters may help distinguish acute kawasaki disease from other febrile illnesses in children

Characteristic

Acute KD

2–10 days

(n = 75)

Subacute KD

13–24 days

(n = 36)

Early Convalescent KD

25–75 days

(n = 43)

Late Convalescent KD

9–49 months

(n = 20)

Acute Febrile Controls

Bacterial origin

(n = 12)

Acute Febrile Controls

Viral origin

(n = 36)

Healthy

Controls

(n = 48)

Male, n (%)

39 (52)

20 (56)

26 (60)

11 (55)

10 (83)

21 (58)

–

Age, years

3.6 (1.8–5.0)

2.9 (1.7–4.6)

3.1 (1.7–4.5)

8.0 (6.7–9.2)

6.2 (4.7–8.2)

2.8 (1.6–5.3)

4.7 (3.0–6.6)

Illness day/month

6.0 d (4.5–7.0)

19 d (16–21)

48 d (34–55)

16 m (14–29)

3.5 d (3.0–4.3)

6.0 d (4.0–6.3)

–

Median lab values

 WBC, ×103/μL

13.7 (10.6–17.3)

7.3 (6.8–9.0)

7.4 (6.0–8.5)

–

12.4 (10.1–14.5)#

8.7 (6.3–11.5)#

–

 PMN, %

56 (45–66)

37 (26–50)

37 (27–42)

–

62 (46–70)

40 (23–54)

–

 ANC, cells/μL

9646 (6693–12,131)

3025 (1953–3950)

2516 (1823–3525)

–

7014 (5565–9444)

3408 (2071–6764)

–

 ESR, mm/h

61 (47–75)

37 (31–57)

17 (9–31)

–

31 (22–40)#

30 (17–39)#

–

 CRP, mg/dL

7.4 (4.7–16.7)

0.3 (0.3–0.8)

0.3 (0.3–0.3)

–

2.2 (1.0–8.6)#

4.1 (2.2–5.0)#

–

 GlycA, μmol/L

808 (693–919)

440 (382–512)

309 (272–377)

341 (319–395)

595 (571–745)

611 (551–702)

319 (290–354)

  1. Median (IQR = Interquartile Range; 25th-75th percentile); KD Kawasaki Disease, d days, m months, WBC white blood cell count, PMN polymorphonuclear cells, ANC absolute neutrophil count, ESR erythrocyte sedimentation rate, CRP C-reactive protein; GlycA, NMR-measured marker of systemic inflammation. #Lab data available for WBC 46 subjects, ESR 42 subjects, CRP 31 subjects
  2. Acute KD samples were taken pre-IVIG treatment. All other KD samples were taken post-IVIG treatment