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Table 4 Comparison between frequencies of different aetiologies among children with non-severe or severe and/or very severe community-acquired pneumonia according to the World Health Organization 2013 criteria

From: Comparison of the frequency of bacterial and viral infections among children with community-acquired pneumonia hospitalized across distinct severity categories: a prospective cross-sectional study

Aetiology

Severity by the World Health Organization 2013 criteria

Non-severe (n = 164)

Severe (n = 17)

p

Subgroups

 Detected

142 (86.6)

14 (82.4)

0.7

 Viral infection

79 (48.2)

5 (29.4)

0.1

 Bacterial infection

63 (38.4)

9 (52.9)

0.2

 Typical bacterial infection

47 (28.7)

7 (41.2)

0.3

 Atypical bacterial infection

16 (9.8)

2 (11.8)

0.7

Pathogens

S. pneumoniae

33 (20.1)

6 (35.3)

0.2

Positive blood culture

6 (3.7)

2 (11.8)

0.2

Positive blood PCR

6 (3.7)

1 (5.9)

0.5

Invasive infectiona

11 (6.7)

2 (11.8)

0.4

H. influenzae

12 (7.3)

1 (5.9)

1.0

M. pneumoniae

10 (6.1)

1 (5.9)

1.0

C. trachomatis

9 (5.5)

-

1.0

M. catarrhalis

4 (2.4)

-

1.0

S. negevensis

2 (1.2)

1 (5.9)

0.3

 Rhinovirus

39 (23.8)

-

0.03

 RSV

33 (20.1)

3 (17.6)

1.0

 Parainfuenza 1, 2, 3

32 (19.5)

3 (17.6)

1.0

 Influenza A, B

14 (8.5)

1 (5.9)

1.0

 Human bocavirus

17 (10.4)

-

0.4

 Adenovirus

9 (5.5)

1 (5.9)

1.0

 Enterovirus

9 (5.5)

1 (5.9)

1.0

 Human metapneumovirus

7 (4.3)

1 (5.9)

0.6

  1. Results in n (%)
  2. RSV respiratory syncytial virus
  3. aInvasive disease was defined as positive blood culture (bacteraemia) and/or positive blood PCR for pneumococcus