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Table 5 Celiac disease risk in relation to maternal infections during early life in all children

From: Maternal and perinatal conditions and the risk of developing celiac disease during childhood

 

Descriptive

    

Exposures

CD Cases

Not CD cases

Bivariate analyses

Multivariable analyses

 

N (%)

N (%)

OR (95 % CI)

P-value

OR (95 % CI)

P-value

Urinary tract infections

      

 No

5 700 (86)

1 667 663 (88)

1.0

 

1.0

 

 Yes

896 (14)

237 935 (13)

1.1 (1.0–1.2)

0.007

1.2 (1.1–1.2)a

<0.001

Other maternal infections

      

 No

6 561 (99)

1 893 642 (99)

1.0

 

1.0

 

 Yes

35 (0.5)

11 956 (0.6)

0.8 (0.6–1.2)

0.32

0.9 (0.7–1.4)a

0.80

urinary tract infections, <35years, Low income

      

 Yes

689 (63)

136 479 (48)

1.0

 

1.0

 

 No

343 (37)

150 895 (53)

0.5 (0.5–0.6)

<0.001

0.5 (0.4–0.6)b

<0.001

  1. aAdjusted for maternal age, disposable income, body mass index, parity, and duration of pregnancy, infant birth weight, sex, and Apgar score and urinary tract infections
  2. bAdjusted for body mass index, parity, pregnancy duration, and premature rupture of the membrane, infant birth weight, sex, Apgar score and other maternal infections