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Table 5 Comparing wild and mutant genotypes of CYP2C9*3 for dose (mg/kg) and drug level (mcg/ml)

From: Frequencies of CYP2C9 polymorphisms in North Indian population and their association with drug levels in children on phenytoin monotherapy

Variables

AA (n = 71)

AC (n = 18)

P value

Dose (mean ± SD)

5.3 ± 1.20

4.8 ± 0.69

0.12

Phenytoin levela (Median)

5.9

18.8

0.009

  1. aNon parametric test applied as variability was high (Wilcoxon rank-sum test)