Table 2 Clinical characteristics of study participants
Variables | Outcome | Unadjusted Odds ratio (CI) | p-value | ||
|---|---|---|---|---|---|
Multi therapy N = 45 (%) | Mono therapy N = 94 (%) | ||||
Age at onset | <1 year | 22 (48.9) | 35 (37.2) | 1.61 (0.79 - 3.31) | 0.193 |
≥1 year | 23 (51.1) | 59 (62.8) | 1 | ||
Duration of epilepsy | <2 years | 4 (8.9) | 17 (18.1) | 1 | |
≥2 years | 41 (91.1) | 77 (81.9) | 2.26 (0.71 – 7.17) | 0.165 | |
Seizure patterna | Generalized | 12 (29.3) | 37 (41.7) | 1 | |
Focal | 24 (58.5) | 35(41.7) | 2.11 (0.92 – 4.86) | 0.078 | |
Epileptic syndrome | 5 (12.2) | 12 (14.3) | 1.28 (0.38 – 4.39) | 0.690 | |
Seizure frequencyb | ≥1seizure/day | 29 (64.5) | 45 (47.9) | 1 | |
≥1 seizure/week | 2 (4.5) | 10 (10.6) | 0.32 (0.06 – 1.55) | ||
≥1 seizure/month | 10 (22.2) | 29 (30.9) | 0.53 (0.23 – 1.24) | 0.317 | |
≤1 seizure/year | 4 (8.8) | 10 (10.6) | 0.63 (0.18 – 2.21) | ||
Neurological deficit | No | 5 (11.1) | 40 (42.5) | 1 | |
Yes | 40 (88.9) | 54 (57.5) | 5.93 (2.15 – 16.36) | <0.001 | |
Symptomatic epilepsy | No | 11 (24.4) | 33 (35.1) | 1 | |
Yes | 34 (75.6) | 61 (64.9) | 1.67 (0.75 – 3.73) | 0.240 | |
Prior history of status epilepticus | No | 28 (62.2) | 75 (79.8) | 1 | |
Yes | 17 (37.8) | 19 (20.2) | 2.40 (1.09 – 5.26) | 0.027 | |
Family history of epilepsy | No | 30 (66.7) | 75 (79.8) | 1 | |
Yes | 15 (33.3) | 19 (20.2) | 1.97 (0.89 – 4.39) | 0.092 | |
Seizure control | Good | 13 (28.9) | 61 (64.9) | 1 | |
Poor | 32 (71.1) | 33 (35.1) | 4.55 (2.10 – 9.84) | <0.001 | |