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Table 2 Infant outcomes of four groups (data from randomisation; n (%) or median (IQR) unless specified)

From: Randomised controlled trial of weaning strategies for preterm infants on nasal continuous positive airway pressure

  Group 1 Group 2 Group 3 Group 4 ANOVA
n = 15 n = 15 n = 15 n = 15 p-value
CLD at 36 weeks 3 (20 %) 4 (27 %) 7 (47 %) 2 (13 %) 0.2
Days respiratory support 21 (9, 33) 26 (20, 38) 30 (24, 33) 24 (10, 35) 0.4
Days hospital stay 50 (39, 58) 53 (41, 71) 64 (50, 78) 53 (48, 66) 0.2
Days to full suck feeds 40 (35, 54) 51 (36, 66) 57 (41, 73) 51 (37, 64) 0.5
Days NCPAP 1 (0, 12) 24 (9, 28) 15 (11, 21) 24 (10, 35) 0.002
Gestational age off NCPAP 31.6 33.9 35.7 34.6 0.04
(30.0, 34.1) (32.1, 35.9) (31.0, 37.6) (31.9, 35.3)
Days HFNC from start of treatment 15 (7, 24)   30 (20, 34)   0.004
Days pressure support 15 (9, 29) 24 (9, 28) 30 (24, 33) 24 (10, 35) 0.1
Gestational age off pressure support 34.0 33.9 35.9 34.6 0.07
(32.7, 35.3) (32.1, 35.9) (33.9, 38.9) (31.9, 35.3)
Gestational age off respiratory support 34.7 34.1 35.9 34.6 0.1
(33.4, 35.3) (33.1, 36.0) (33.9, 38.9) (31.9, 35.3)
Gestational age at full suck feeds 36.9 37.1 39.6 37.3 0.1
(36.4, 38.0) (36.1, 40.6) (37.1, 44.0) (36.6, 39.1)
Gestation at discharge 37.7 37.9 39.9 38.3 0.1
(36.9, 39.1) (37.1, 40.1) (37.9, 45.0) (36.9, 39.7)
Postnatal growth failure 9 (60 %) 9 (60 %) 7 (47 %) 7 (47 %) 0.8
Weight at 36 weeks - g (sd) 2158 (411) 2044 (390) 2042 (338) 2128 (532) 0.4
Days caffeine 24 (24) 34 (30) 40 (22) 39 (33) 0.2
Grade 2 apnea (required IPPV) 0 1 (7 %) 0 0 0.4
Necrotising enterocolitis 0 1 (7 %) 0 0 0.4
Treated ductus arteriosus 2 (13 %) 5 (33 %) 4 (27 %) 1 (7 %) 0.2
Retinopathy of prematurity 7 (47 %) 6 (40 %) 6 (40 %) 6 (40 %) 0.6
Laser therapy 1 (7 %) 0 0 1 (7 %) 0.6
Nasal injury 0 0 1 (7 %) 1 (7 %) 0.4
Withdrawn 0 6 (40 %) 1 (7 %) 0 0.01