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Table 2 Characteristics of all 4 neonates with SCFN

From: Subcutaneous fat necrosis in neonates with hypoxic ischaemic encephalopathy registered in the Swiss National Asphyxia and Cooling Register

SCFN

Case 1

Case 2

Case 3

Case 4

Sex

Female

Female

Male

Female

Gestationalage[weeks]

38 2/7

40 2/7

39 1/7

40 0/7

Birth weight [grams]

3920

3480

3400

3190

Mode of delivery

Emergency caesarian section

Instrumental delivery

Instrumental delivery

Emergency caesarian section

Age at appearance of SCFN [days]

16

3

6

4

Cooling method applied

Passive plus ice packs

Passive plus ice packs

Active (Criticool System)

Active (Criticool System)

Localization of SCFN

Left scapula region and dorsal upper arm

Back

Back

Upper back

Appearance of SCFN

Red nodules, plaques

Red nodules, plaques

Palpablenodules, plaques

Red nodules, plaques

Diagnosis by

Neonatologist

Neonatologist

Neonatologist

Neonatologist

Therapy

Conservative

Conservative

Conservative

Hydration, low calcium formula, no vitamin D supplementation, analgesia

Thrombocytopenia

No

No

No

No

Hypoglycemia

No

No

No

No

Calcium level ionized (total) [mmol/l]

1.41 (2.49)

1.33

1.5

1.54 (2.77)

Follow-up

Yes

Yes

Yes

Yes

Who

Pediatrician, pediatric surgeon

Pediatrician

Pediatrician

Pediatrician, endocrinologist

Examination

Clinical follow-up

Clinical follow-up and calcium level

Clinical follow-up

Clinical follow-up, calcium level and ultrasound of kidneys

  1. SCFN subcutaneous fat necrosis calcium level: routinely ionized calcium is measured