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Table 3 Bloodstream infection-associated mortality

From: Trends in paediatric bloodstream infections at a South African referral hospital

BSI-associated mortality Number (n) Percentage (%) p-value  
Total BSI-associated deaths 176 100 -  
Male 97 55.1 0.49
Median age (months) IQR 7.2 IQR 3–14.7 -
HIV status    
- Positive 34 19.3  
- Negative 87 49.4 0.03
- Unknown 55 31.3  
Onset of BSI #    
- Community-acquired 75/460 16.3 0.002
- Hospital-acquired 101/404 25  
Factors associated with mortality from BSI
Variable assessed Univariate analysis (p-value) Multivariate analysis (p-value) Odds ratio 95% CI
Length of stay prior to BSI onset <0.001 0.11 - -
Age category 0.13 0.44 - -
Gender 0.49 0.32 - -
HIV status (positive) 0.03 0.02 1.74 1.1 - 2.8
Year of BSI 0.89 0.78 - -
Place of BSI onset (hospital-acquired) 0.002 0.04 1.43 1.1 - 2.0
Type of BSI pathogen 0.001 0.03   
- Fungal    2.10 1.1 – 4.2
- Gram negative    1.88 1.2 – 2.9
Mono- vs poly-microbial BSI 0.72 0.6 - -
ICU vs general ward at BSI onset <0.001 0.001 2.93 1.9 – 4.4
Antimicrobial resistance 0.06 0.83 - -
  1. BSI = bloodstream infection; ICU = intensive care unit; #CA-BSI = BC submitted within first 72 hours of admission; HA-BSI = BC submitted > 72 hours after admission. To determine factors associated with mortality from BSI and antimicrobial resistance, binary logistic regression analyses were performed. A p-value below 0.05 was considered statistically significant.