Table 2 Microbiological profile of paediatric bloodstream infection episodes (n = 864)
From: Trends in paediatric bloodstream infections at a South African referral hospital
BSI episodes | n | % | Total pathogens isolated from 864 BSI episodes* | Â | |
|---|---|---|---|---|---|
Monomicrobial | 818 | 94.7 | 914 | Â | |
Polymicrobial | Â | Â | Â | ||
- 2 pathogens | 42 | 4.8 | Â | ||
- 3 pathogens | 4 | 0.5 | Â | ||
Gram negatives | Organism | n = 550 | % of Gram negatives | Organism rank* | |
Enterobacteriaceae | K. pneumoniae | 154 | 28% | 1 | |
| Â | E. coli | 97 | 18% | 3 | |
| Â | E. cloacae | 30 | 5% | 7 | |
| Â | S. marcescens | 19 | 3% | 10 | |
| Â | Salmonella spp | 18 | 3% | Â | |
| Â | (non-typhi) | Â | Â | Â | |
| Â | Klebsiella spp | 12 | 2% | Â | |
| Â | Other (9 different genera) | 30 | 5% | Â | |
| Â | Total | 360 | 65% | Â | |
Non-fermenting Gram negative bacilli | A. baumannii | 78 | 14% | 5 | |
| Â | P. aeruginosa | 20 | 4% | 9 | |
| Â | Acinetobacter spp | 16 | 3% | Â | |
| Â | S. paucimobilis | 9 | 2% | Â | |
| Â | Other (9 different genera) | 20 | 4% | Â | |
| Â | Total | 143 | 26% | Â | |
Other Gram negative organisms | H. influenzae | 23 | 4% | 8 | |
| Â | N. meningitidis | 11 | 2% | Â | |
| Â | Other (6 different genera) | 13 | 3% | Â | |
| Â | Total | 47 | 9% | Â | |
Gram positives | Organism | n = 296 | % of Gram positives | Organism rank* | |
Staphlylococci | Staphylococcus aureus | 131 | 44% | 2 | |
Streptococci | Streptococcus pneumoniae | 91 | 31% | 4 | |
Group B Streptococcus | 19 | 6% | 10 | ||
Enterococci | Enterococcus spp | 46 | 16% | 6 | |
Other Gram positive organisms | Other (4 different genera) | 9 | 3% | Â | |
Fungi | Organism | n = 68 | % of Fungi | Organism rank* | |
Candida spp | Candida albicans | 21 | 31% | 9 | |
Candida tropicalis | 12 | 18% | Â | ||
Candida parapsilosis | 9 | 13% | Â | ||
Candida glabrata | 3 | 4% | Â | ||
Candida krusei | 2 | 3% | Â | ||
All other candida spp | 18 | 27% | Â | ||
Other fungi | Aspergillus spp, | 1 | 4% | Â | |
Trichosporon spp, | 1 | Â | |||
unidentified yeast | 1 | Â | |||
BSI pathogens (n = 914) by type and place of infection onset for 864 BSI episodes | |||||
Community-acquired (CA-BSI) pathogens | Hospital-acquired (HA-BSI) pathogens | ||||
n = 477 | n = 437 | ||||
CA-BSI ward pathogens # | n = 433 | % | HA-BSI ward pathogens # | n = 275 | % |
- Staphylococcus aureus | 90 | 21 | - Klebsiella pneumoniae | 86 | 31 |
- Streptococcus pneumoniae | 81 | 19 | - Candida spp | 28 | 10 |
- Escherichia coli | 67 | 15 | - Acinetobacter baumanni | 26 | 10 |
- Other | 195 | 45 | - Other | 135 | 49 |
CA-BSI ICU pathogens # | n = 44 | % | HA-BSI ICU pathogens # | n = 162 | % |
- Escherichia coli | 9 | 21 | - Acinetobacter baumanni | 42 | 26 |
- Klebsiella pneumoniae | 7 | 16 | - Klebsiella pneumoniae | 33 | 20 |
- Staphylococcus aureus | 5 | 11 | - Candida spp | 22 | 14 |
- Other | 23 | 52 | - Other | 65 | 40 |