Table 2 Infectious episode rates by subject attributes
Factor | A. Any infectious episode rate ratios (RR) | B. Febrile infectious episode rate ratios (RR) | C. Non-febrile infectious episode rate ratios (RR) | ||||||
|---|---|---|---|---|---|---|---|---|---|
RR | 95%CI | p-value | RR | 95%CI | p-value | RR | 95%CI | p-value | |
Site | |||||||||
US-Colorado | 1.00 | ref | 1.00 | ref | 1.00 | ref | |||
US-Georgia | 1.18 | 1.14 – 1.22 | 1.30 | 1.23 – 1.37 | 1.12 | 1.07 – 1.16 | |||
US-Washington | 1.05 | 1.02 – 1.09 | 1.03 | 0.97 – 1.09 | 1.06 | 1.02 – 1.10 | |||
Europe – Finland | 1.50 | 1.46 – 1.54 | 1.95 | 1.87 – 2.04 | 1.28 | 1.24 – 1.32 | |||
Europe – Germany | 1.40 | 1.34 – 1.45 | 1.80 | 1.69 – 1.92 | 1.19 | 1.13 – 1.25 | |||
Europe - Sweden | 1.42 | 1.39 – 1.46 | <0.001 | 2.39 | 2.30 – 2.49 | <0.001 | 0.94 | 0.91 – 0.97 | <0.001 |
Gender of child | |||||||||
Female | 1.00 | ref | 1.00 | ref | 1.00 | ref | |||
Male | 1.04 | 1.02 – 1.05 | <0.001 | 1.03 | 1.00 – 1.05 | 0.02 | 1.05 | 1.03 – 1.07 | <0.001 |
First degree relative with T1D | |||||||||
No | 1.00 | ref | 1.00 | ref | 1.00 | ref | |||
Yes | 1.01 | 0.98 – 1.04 | 0.40 | 0.97 | 0.93 – 1.01 | 0.19 | 1.05 | 1.01 – 1.09 | 0.02 |
HLA-DR-DQ genotype | |||||||||
DR4-DQ8/DR4-DQ8 | 1.00 | ref | 1.00 | ref | 1.00 | ref | |||
DR3-DQ2/DR4-DQ8 | 1.02 | 1.00 – 1.04 | 0.99 | 0.96 – 1.02 | 1.05 | 1.02 – 1.08 | |||
DR4-DQ8/DR8-DQ4 | 0.97 | 0.94 – 0.99 | 0.97 | 0.93 – 1.01 | 0.96 | 0.93 – 1.00 | |||
DR3-DQ2/DR3-DQ2 | 0.99 | 0.97 – 1.01 | 0.92 | 0.89 – 0.95 | 1.05 | 1.02 – 1.09 | |||
HLA-FDR specifica | 0.98 | 0.93 – 1.03 | <0.001 | 1.01 | 0.94 – 1.09 | <0.001 | 0.95 | 0.89 – 1.02 | <0.001 |