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Table 3 Clinical presentation at baseline, 3, 6 and 12 months

From: Improved insulin sensitivity and body composition, irrespective of macronutrient intake, after a 12 month intervention in adolescents with pre-diabetes; RESIST a randomised control trial

 

Baseline

3 months

6 months

12 months

n = 111

n = 106

n = 100

n = 85

Acanthosis nigricans present

94

(84.7)

88

(83.8)*

79

(85.9)*

61

(76.3)*

Pre-diabetes

14

(12.6)

19

(17.9)

  

10

(12.1)*,**

Dyslipidaemia

61

(55.0)*

57

(54.3)*

51

(53.7)|

32

(28.8)*

(HDL-C <1.03 mmol/L and/or triglycerides ≥1.7 mmol/L)

SBP and/or DBP ≥90 percentile

49

(44.1)

41

(38.7)

30

(30.6)*

37

(43.5)

Elevated liver enzymes (ALT and/or GGT ≥1.5 upper limit of 30 U/L)

22

(20.0)*

21

(20.4)*

17

(17.3)*

14

(12.6)*

Microalbuminuria

9

(8.5)*

9

(8.9)*

9

(9.5)*

9*

(8.1)*

(Urine/albumin/creatinine, Girls: 3.5 to 25 mg/mmol, Boys: 2.5 to 25 mg/mmol)

  1. *1 missing value, †2 missing values, †3 missing values, †5 missing values, | 8 missing values **including one adolescent diagnosed with type 2 diabetes.
  2. Values are n (%).