Serum 25(OH)D concentrations and atopic diseases at age 10: results from the GINIplus and LISAplus birth cohort studies

Table 5 Odds ratio estimates and 95% confidence intervals for the association of vitamin D status and eczema, stratified by age of onset and duration of eczema

		OR (CI)
		1. Quartile	2. Quartile	3. Quartile	4. Quartile	Continuous [per 10 nmol/l]
Never vs. only when younger than 6 years	Cases/Non-diseased (% Cases)	102/430 (19%)	107/430 (20%)	91/420 (18%)	104/433 (19%)	404/1713 (19%)
Never vs. only when younger than 6 years	Adjusted model¹	1	1.06 (0.78;1.44)	0.93 (0.68;1.28)	1.04 (0.76;1.43)	1.02 (0.97;1.07)
Never vs. only when 6 years or older	Cases/Non-diseased (% Cases)	19/430 (4%)	25/430 (5%)	32/420 (7%)	20/433 (4%)	96/1713 (5%)
Never vs. only when 6 years or older	Adjusted model¹	1	1.28 (0.69;2.39)	1.70 (0.94;3.08)	1.08 (0.56;2.08)	1.04 (0.94;1.14)
Never vs. persistent cases	Cases/Non diseased (% Cases)	52/430 (11%)	64/430 (13%)	61/420 (13%)	70/433 (14%)	247/1713 (13%)
Never vs. persistent cases	Adjusted model¹	1	1.16 (0.78;1.722)	1.16 (0.78;1.74)	1.36 (0.92;2.01)	1.09^* (1.03;1.16)

¹Outcome = Vitamin D concentration + age + sex + location of study + study + breastfeeding + BMI + highest parental education + single parent status + family history.
The OR estimates and 95% CI for the association of vitamin D status (serum 25(OH)D concentration [10 nmol/l]) and eczema, stratified by age of onset and duration of eczema (never versus early onset but transient, late onset but transient and persistent cases) are displayed. The asterisk indicate significant results at p < 0.05.

ISSN: 1471-2431