Skip to main content

Table 1 Reporting of Data Monitoring Committees (DMCs) or Interim Analysis or Early Termination: Data on Included Randomized Controlled Trials (RCTs), and Total Number of Published RCTs, per Journal, from 2005 to 2007*

From: A systematic review of the reporting of Data Monitoring Committees' roles, interim analysis and early termination in pediatric clinical trials

Journal

RCTs Reporting DMC or Interim/Total RCTs

RCTs Reporting Early Termination/Total RCTs

General Journals

  

   BMJ

3/62 (5%)

1/62 (2%)

   JAMA

11/24 (46%)

1/24 (4%)

   Lancet

23/83 (28%)

9/83 (11%)

   N Engl J Med

31/80 (39%)

3/80 (4%)

   Total

68/249 (27%)

14/249 (6%)

Pediatric Journals

  

   Arch Dis Child

2/37 (5%)

2/37 (5%)

   Arch Ped Adolesc Med

4/61 (7%)

2/61 (3%)

   J Pediatr

7/88 (8%)

3/88 (3%)

   Pediatrics

24/213 (11%)

11/213 (5%)

   Total

37/399 (9%)

18/399 (5%)

  1. *The denominator refers to the total number of pediatric trials for each journal during the studied time period, which was obtained using Medline's filters (publication type "randomized controlled trial" and age category "0-18 years").
Back to article page

BMC Pediatrics

ISSN: 1471-2431

Contact us