Selected hematologic and biochemical measurements in African HIV-infected and uninfected pregnant women and their infants: the HIV Prevention Trials Network 024 protocol

Table 3 Laboratory values among HIV-infected and HIV-uninfected pregnant women at 36 weeks gestation

Laboratory Parameter	HIV-infected				HIV-uninfected				p value
	n	Mean ± SD	95% CI		n	Mean ± SD	95% CI
			Lower	Upper			Lower	Upper
Red blood cell count 10⁶/μL	1643	3.8 ± 0.6	2.78	4.94	280	3.9 ± 0.7	2.865	5.34	< 0.0001
Hemoglobin g/dl	1642	10.7 ± 1.4	7.9	13.2	280	11.3 ± 1.3	9	13.95	< 0.0001
Hematocrit %	1643	31.7 ± 4.3	23.3	39.5	280	33.3 ± 4.2	25.9	41.85	< 0.0001
Platelets 10³/μL	1642	209.8 ± 79.1	88	402	280	182.9 ± 64.8	86.5	344.5	< 0.0001
White blood cell count 10³/μL	1639	6.1 ± 2.0	3.1	10.2	280	6.7 ± 2.1	3.8	11.2	< 0.0001
Lymphocytes %	1633	31.4 ± 8.7	16.7	50.5	274	31.8 ± 8.4	18.1	53.6	0.5
Monocytes %	1633	8.4 ± 5.1	2.1	21.9	274	7.5 ± 5.3	1.1	23.1	0.01
Granulocytes %	1632	60.1 ± 11.0	32.1	77.8	274	60.7 ± 10.8	32.6	76.5	0.4
CD4+ T lymphocyte count cells/μμL	1459	399.8 ± 222.7	65	901	166	786.0 ± 266.4	368	1325	< 0.0001
CD8+ T lymphocyte count cells/μL	1459	776.2 ± 336.3	293	1618	166	506.8 ± 218.5	216	1106	< 0.0001
CD4+ T lymphocyte %	185	24.2 ± 10.4	4	43	49	45.0 ± 9.3	28	66	< 0.0001
CD8+ lymphocyte %	185	54.0 ± 12.5	32	79	49	31.1 ± 7.4	21	43	< 0.0001
Total T lymphocytes as a % of all lymphocytes	173	77.5 ± 9.7	57	92	43	74.1 ± 9.6	54	90	0.04

Note: Indicates t-test P values comparing laboratory values between HIV-infected and HIV-uninfected women at 36 weeks gestation

ISSN: 1471-2431