Selected hematologic and biochemical measurements in African HIV-infected and uninfected pregnant women and their infants: the HIV Prevention Trials Network 024 protocol

Table 2 Laboratory values among HIV-infected and HIV-uninfected pregnant women at 20–24 weeks gestation

Laboratory Parameter	HIV-infected				HIV-uninfected				p value*
	n	Mean ± SD	95% CI		n	Mean ± SD	95% CI
			Lower	Upper			Lower	Upper
Red blood cell count 10⁶/μL	2266	3.6 ± 0.5	2.56	4.65	367	3.8 ± 0.6	2.65	4.92	< 0.0001
Hemoglobin g/dl	2262	10.1 ± 1.4	7.1	12.7	367	11.0 ± 1.3	8.2	13.2	< 0.0001
Hematocrit %	2265	29.9 ± 4.2	21.4	37.7	367	32.3 ± 4.6	23.8	39.4	< 0.0001
Platelets 10³/μL	2267	231.6 ± 79.9	102	410	367	204.3 ± 64.9	97	350	< 0.0001
White blood cell count 10³/μL	2266	6.1 ± 2.0	2.9	10.3	366	6.9 ± 1.9	3.3	11.1	< 0.0001
Lymphocytes %	2197	31.0 ± 9.9	16.4	58.1	358	31.5 ± 8.7	19	57	0.4
Monocytes %	2197	8.1 ± 5.0	1.9	20.9	358	6.8 ± 4.4	1.9	17	< 0.0001
Granulocytes %	2198	60.7 ± 12.5	22.8	78.6	358	61.7 ± 10.8	28.6	77.5	0.1
CD4+ T lymphocyte count cells/μL	2072	374.4 ± 214.6	64	899	246	809.6 ± 257.9	344	1366	< 0.0001
CD8+ T lymphocyte count cells/μL	2072	771.1 ± 357.6	276	1674	246	513.5 ± 196.8	262	1002	< 0.0001
CD4+ T lymphocyte %	287	23.3 ± 10.7	5	46	55	47.6 ± 8.4	33	65	< 0.0001
CD8+ T lymphocyte %	287	55.4 ± 15.3	26	83	55	31.7 ± 8.4	18	50	< 0.0001
Total T lymphocytes as a % of all lymphocytes	235	74.5 ± 14.4	21	94	47	75.6 ± 8.3	60	93	0.6

*P values by Student's t test comparing laboratory values of HIV-infected and HIV-uninfected pregnant women at 20–24 weeks gestation.

ISSN: 1471-2431