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Table 1 Craniopharyngioma before surgery

From: Childhood craniopharyngioma: greater hypothalamic involvement before surgery is associated with higher homeostasis model insulin resistance index

  Hypothalamic involvement    
Grade 0 1 2 0 vs 1 0 vs 2 1 vs 2
     P P P
Age, years 6.5 ± 4.3 (7) 8.1 ± 2.8 (8) 9.4 ± 3.1 (12)    
Height, SDS 0.46 ± 1.8 (7) -1.1 ± 1.1 (8) -0.57 ± 1.1 (12) <0.04   
BMI, zs 0.20 ± 2.0 (7) 0.58 ± 1.9 (8) 1.5 ± 1.3 (12)    
Glucose, mmol/L 4.4 ± O.25 (5) 4.3 ± 0.6 (7) 5.1 ± 0.6 (10)   0.02 <0.02
Insulin, mIU/L 5.1 ± 2.4 (7) 5.4 ± 3.3 (8) 12.0 ± 11.8 (11)   <0.05 <0.03
HOMA 1.31 ± 0.6 (5) 1.28 ± 0.9 (7) 3.65 ± 3.5 (9)   0.02 <0.03
IGF-1, zs -2.8 ± 1.7 (7) -3.0 ± 3.1 (8) -2.1 ± 2.2 (12)    <0.03
Leptin, μg/L 5.6 ± 2.6 (5) 7.2 ± 4.5 (8) 14.0 ± 9.8 (12)    
sOB-R, μg/L 72 ± 37 (2) 70 ± 35 (8) 50 ± 27 (7)    
Free leptin index 12.7 ± 13 (2) 12.4 ± 9.O (8) 34 ± 33 (7)    
Ghrelin, ng/L 2256 ± 331 (2) 1091 ± 251 (5) 1083 ± 222 (6) 0.05 <0.05  
  1. mean ± SD
  2. Number in parentheses indicate the effectives