Table 1 Craniopharyngioma before surgery
Hypothalamic involvement | ||||||
|---|---|---|---|---|---|---|
Grade | 0 | 1 | 2 | 0 vs 1 | 0 vs 2 | 1 vs 2 |
P | P | P | ||||
Age, years | 6.5 ± 4.3 (7) | 8.1 ± 2.8 (8) | 9.4 ± 3.1 (12) | |||
Height, SDS | 0.46 ± 1.8 (7) | -1.1 ± 1.1 (8) | -0.57 ± 1.1 (12) | <0.04 | ||
BMI, zs | 0.20 ± 2.0 (7) | 0.58 ± 1.9 (8) | 1.5 ± 1.3 (12) | |||
Glucose, mmol/L | 4.4 ± O.25 (5) | 4.3 ± 0.6 (7) | 5.1 ± 0.6 (10) | 0.02 | <0.02 | |
Insulin, mIU/L | 5.1 ± 2.4 (7) | 5.4 ± 3.3 (8) | 12.0 ± 11.8 (11) | <0.05 | <0.03 | |
HOMA | 1.31 ± 0.6 (5) | 1.28 ± 0.9 (7) | 3.65 ± 3.5 (9) | 0.02 | <0.03 | |
IGF-1, zs | -2.8 ± 1.7 (7) | -3.0 ± 3.1 (8) | -2.1 ± 2.2 (12) | <0.03 | ||
Leptin, μg/L | 5.6 ± 2.6 (5) | 7.2 ± 4.5 (8) | 14.0 ± 9.8 (12) | |||
sOB-R, μg/L | 72 ± 37 (2) | 70 ± 35 (8) | 50 ± 27 (7) | |||
Free leptin index | 12.7 ± 13 (2) | 12.4 ± 9.O (8) | 34 ± 33 (7) | |||
Ghrelin, ng/L | 2256 ± 331 (2) | 1091 ± 251 (5) | 1083 ± 222 (6) | 0.05 | <0.05 | |