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Table 5 Risk factors for death among children with seizures

From: The incidence, aetiology and outcome of acute seizures in children admitted to a rural Kenyan district hospital

Risk factors for death Deaths, (%) Survivors, (%) Crude Odds ratio (95% CI) P-value Adjusted odds ratio (95% CI) P value
Median (IQR) duration of illness, days 3 (1–4) 2 (1–3) - 0.170 - -
Median age (IQR), months 17(3–33) 25(13–42) - 0.048 - -
Focal seizures 8/25 (32.0) 149/839(17.8) 2.18(0.80, 5.45) 0.069 - -
Status epilepticus 12/28 (42.9) 86/872 (9.9) 6.85(2.85, 16.0) <0.001 - -
Coma 14/28 (50.0) 73/872 (8.4) 11.0(4.62, 25.7) <0.001 10.3(3.21, 33.1) <0.001
Severe wasting 4/28 (14.3) 8/872 (0.9) 18.0(3.67, 72.3) <0.001 - -
Severe anaemia 4/28 (14.3) 52/872 (6.0) 2.63(0.64, 8.05) 0.073 - -
Acidosis 16/20 (80.0) 125/381(32.8) 8.19(2.56, 34.2) <0.001 7.19(1.94, 26.7) 0.003
Hypoglycaemia 6/27 (22.2) 21/837 (2.5) 11.1(3.30, 33.3) <0.001 7.06(1.73, 28.7) 0.006
Hyperkalaemia 5/24 (20.8) 32/414 (7.7) 3.14(.86, 9.45) 0.025 - -
Hypokalaemia 2/24 (8.3) 14/414 (3.4) 2.60(0.27, 12.4) 0.209 - -
Hyponatraemia 2/24 (8.3) 12/414 (2.9) 3.05(0.31, 15.0) 0.141 - -
Impaired renal function 14/24 (58.3) 46/383 (12.0) 10.3(3.94, 27.2) <0.001 - -
Bacteraemia 4/27 (14.8) 19/855 (2.2) 7.65(1.75, 25.6) <0.001 16.9(3.39, 33.1) 0.001
Malaria 11/28 (39.3) 468/872(53.7) 0.56(0.23, 1.28) 0.133 - -
Respiratory tract infections 0/28 (0) 138/872(16.4) - 0.022 - -
Gastroenteritis 1/28 (3.6) 38/872 (4.4) 0.81(0.02, 5.42) 0.841 - -
Pyogenic meningitis 4/28 (14.3) 20/872 (2.3) 7.1(1.63, 23.5) <0.001 - -
Neonatal sepsis 2/28 (7.1) 31/872 (3.6) 2.08(0.23, 8.98) 0.320 - -
Hypoxic ischaemic encephalopathy 2/28 (7.1) 3/872 (0.3) 22.3(1.77, 200) <0.001 - -