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Table 1 Basic demographic data, HIV staging, weight categorization and previous TB episodes recorded at the time of HAART initiation, comparing those treated for TB to those not treated for TB

From: Clinical presentation and outcome of Tuberculosis in Human Immunodeficiency Virus infected children on anti-retroviral therapy

 

All children who received HAART

Treated for TB during study period

Not treated for TB during study period

p-value

Total number

290 (100%)

140#‡ (100%)

150## (100%)

 

Gender

    

   Male

143 (49%)

67 (48%)

76 (51%)

0.43

Age (months)

    

Range/median

1–160/23.5

2–140/19

1–160/33.5

0.08

WHO HIV staging*

    

CD4 depletion

    

   not significant

22 (8%)

4 (3%)

18 (12%)

NA

   mild

26 (9%)

9 (6%)

17 (11%)

0.14

   advanced

31 (11%)

10 (7%)

21 (14%)

0.06

   severe

211 (73%)

117 (84%)

94 (63%)

<0.001

Clinical stage

    

   II

15 (5%)

1 (1%)

14 (9%)

NA

   III

128 (44%)

50 (36%)

78 (52%)

<0.01

   IV

144 (50%)

89 (63%)

55 (37%)

<0.001

   Unknown

3 (1%)

0 (0%)

3 (2%)

NA

Weight categories

    

   <60% EWA**

43 (15%)

29 (21%)

14 (9%)

<0.01

   60–80% EWA

110 (38%)

64 (46%)

46 (31%)

<0.01

   80–100% EWA

92 (32%)

34 (24%)

58 (39%)

<0.01

   >100% EWA

25 (9%)

6 (4%)

19 (13%)

0.01

   Unknown

20 (7%)

7 (5%)

13 (8%)

0.22

Previous TB

    

   1 episode

76 (26%)

19 (14%)

57 (38%)

<0.001

   ≥2 episodes

12 (4%)

7 (5%)

5 (3%)

NA

  1. *WHO, World Health Organization immunological classification of HIV-associated immunodeficiency in infants and children, 2006
  2. **EWA, expected weight for age
  3. # Includes 4 children subsequently excluded due to incomplete data
  4. ## Includes 5 children with BCG disease only, who were excluded from further TB analysis
  5. NA – not applicable, sample proportions too small for Z test