Table 3 Quality assessment of included trials
Included Trial | Gunn 1998 | Gluckman 2005 | Shankaran 2002 | Shankaran 2005 | Eicher 2005 |
|---|---|---|---|---|---|
Adequacy of method of randomisation | Yes Computer generated | Yes Computer generated, block | Yes Computer generated, block | Yes Computer generated, block | Yes Central website, block |
Concealment of allocation | Yes Sealed opaque envelopes | Yes Sealed opaque envelopes | Yes Central data- coordinating center | Yes Central data- coordinating center | Yes Central website |
Blinding of intervention | None Due to nature of intervention | None Due to nature of intervention | None Due to nature of intervention | None Due to nature of intervention | None Due to nature of intervention |
Blinding of outcome assessors | Not robustly | Yes | No | Yes | Unknown |
Completeness of follow-up | Yes (96%) | Yes (93%) | Follow-up not reported# | Yes (98%) | No (68%)# |