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Table 2 Normalisation of blood volume for body size parameters. Plasma volume (PV), red cell volume (RCV) and blood volume (BV) normalized for height (L), body weight (BW), body surface area (BSA) or lean body mass (LBM) as well as the F-cell ratio of the male and female study population. Data is presented as mean and standard deviation and was analysed with a Mann-Whitney U-test

From: A reference frame for blood volume in children and adolescents

Gender

 

Male

Female

 

N

 

42

35

P

PV/height (L/m)

 

1.30 ± 0.44

1.16 ± 0.39

NS

PV/BW (ml/kg)

 

52.3 ± 8.3

47.9 ± 7.7

0.011

PV/BSA (L/m2)

 

1.5 ± 0.28

1.38 ± 0.24

0.026

PV/LBM (ml/kg)

 

57.8 ± 9.1

58.3 ± 10.5

NS

RCV/height (L/m)

 

0.63 ± 0.21

0.55 ± 0.22

NS

RCV/BW (ml/kg)

 

25.3 ± 4.7

22.4 ± 4.88

0.002

RCV/BSA (L/m2)

 

0.74 ± 0.15

0.65 ± 0.17

0.01

RCV/LBM (ml/kg)

 

27.9 ± 4.3

26.9 ± 4.9

NS

BV/height (L/m)

All

1.93 ± 0.62

1.68 ± 0.58

NS

 

1

1.53 ± 0.31

1.17 ± 0.23

0.001

 

2–4

2.30 ± 0.51

1.91 ± 0.35

NS

 

5

2.75 ± 0.53

2.28 ± 0.41

NS

  

0.000a

0.000a

 
 

Ref. Boer (7)

2.83 ± 0.32

2.46 ± 0.23

 

BV/BMI (ml/kg/m2)

All

143 ± 47.6

121 ± 47.2

0.035

 

1

119 ± 37.5

81.9 ± 25.9

0.001

 

2–4

164 ± 46.3

131 ± 14.3

NS

 

5

196 ± 13.4

173 ± 36.2

NS

  

0.000a

0.000a

 

BV/BW (ml/kg)

All

77.4 ± 11.0

68.7 ± 11.0

0.001

 

1

78.5 ± 10.6

74.9 ± 8.5

NS

 

2–4

75.9 ± 12.0

63.4 ± 5.2

0.008

 

5

76.4 ± 11.6

63.7 ± 13.7

NS

  

NSa

0.007a

 
 

7

71.1 ± 8.8

65.2 ± 9.4

 

BV/BSA (L/m2)

All

2.254 ± 0.378

1.989 ± 0.351

0.004

 

1

2.059 ± 0.244

1.789 ± 0.231

0.002

 

2–4

2.409 ± 0.353

2.007 ± 0.145

0.016

 

5

2.711 ± 0.381

2.292 ± 0.429

0.045

  

0.001a

0.003a

 
 

7

2.68 ± 0.27

2.40 ± 0.28

 

BV/LBM (ml/kg)

All

83.4 ± 13.8

84.2 ± 14.9

NS

 

1

82.0 ± 7.1

84.2 ± 14.7

NS

 

2–4

88.5 ± 13.5

80.9 ± 11.4

NS

 

5

93.2 ± 15.6

84.2 ± 15.2

NS

  

NSa

NSa

 
 

7

88.2 ± 8.7

88.4 ± 8.7

 

F-Cell ratio

 

0.83 ± 0.10

0.85 ± 0.08

NS

  1. P < 0.05: significance level for differences between male and female population
  2. All = combined data of different pubertal stages
  3. 1: prepubertal stage (ref. Tanner)
  4. 2–4: pubertal stage (ref. Tanner)
  5. 5: postpubertal stage (ref. Tanner)
  6. 7: ref. P. Boer
  7. a: significance level (MWU) between the different pubertal stages