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Table 1 Results of NPD measurements in CF patients, heterozygotes for 1 CF mutation and healthy controls.

From: The CF-CIRC study: a French collaborative study to assess the accuracy of Cystic Fibrosis diagnosis in neonatal screening

Variables CF (n = 37) Htz (n = 37) Ctrls (n = 29) p CF vs. Htz p CF vs. Ctrls p Htz vs. Ctrls
Baseline NPD(mV) -47(2.6) -15.5(1.3) -15(1.5) <0.0001 <0.0001 0.9
Δamiloride (mV) 24(2.2) 6.2(0.9) 7.1(1.2) <0.0001 <0.0001 0.69
Δchloride-free(mV) 0.5(1.1) -6(0.8) -10.1(1.5) <0.0001 <0.0001 0.01
Δisoproterenol (mV) -1(0.3) -2.5(0.3) -5(0.6) 0.004 <0.0001 0.003
ΔCl-free-Isoproterenol (mV) 1(1.3) -8.2(0.9) -15(1.7) 0.008 <0.0001 0.0002
  1. Data are presented as mean (SEM)
  2. Htz: heterozygotes; Ctrls: healthy controls