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Table 1 Case Definition.

From: Subacute Sclerosing Panencephalitis: Results of the Canadian Paediatric Surveillance Program and review of the literature

Definite Case

A. High titres of serum antibodies against measles virus and the presence of oligoclonal measles virus antibodies in CSF (Serum: CSF measles antibody ratio indicative of intrathecal antibody production).

And/or

B. Measles virus antigen detected in brain tissue by biopsy or at autopsy

Suspect Case

A. Typical clinical history: usually insidious onset of mental deterioration, followed (usually within a few months) by motor dysfunction, final progressive decerebration and untimely death

And

B. Typical EEG changes

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BMC Pediatrics

ISSN: 1471-2431

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