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Table 3 Factors associated with parental concerns, specialist referral, impact of behaviour on the family, and parental anxiety, at 3 years, adjusted for centre and congenital infection status(Total N = 705)

From: Association between congenital toxoplasmosis and parent-reported developmental outcomes, concerns, and impairments, in 3 year old children

  Odds ratio for outcome (95% confidence interval)
EXPOSURES Any concerns5 Any referral Behaviour impact4 Parental anxiety3
Before birth     
1) Congenital toxoplasmosis (reference = uninfected) 0.98 (0.95, 1.01) 2.00 (0.90, 4.45) 0.55 (0.22, 1.39) 3.01 (1.84, 4.94)
2) Maternal Age 1 0.97 (0.92, 1.03) 0.96 (0.89, 1.05) 0.98 (0.90, 1.07) 0.98 (0.93, 1.03)
3) Parity 1 0.96 (0.81, 1.15) 1.05 (0.72, 1.54) 0.98 (0.66, 1.44) 1.26 (1.06, 1.50)
4) Maternal Education 1 0.91 (0.73, 1.14) 0.77 (0.51, 1.16) 1.18 (0.81, 1.74) 0.82 (0.65, 1.04)
5) Mother born outside country 2 (no = reference) 1.59 (0.84, 3.01) 0.82 (0.18, 3.79) 2.20 (0.86, 5.60) 1.06 (0.51, 2.21)
6) Child's gender (male = reference) 1.89 (1.22, 2.93) 0.83 (0.39, 1.73) 0.99 (0.50, 1.96) 1.26 (0.81, 1.94)
7) Duration of prenatal treatment (wks) 0.98 (0.96, 1.00) 1.00 (0.96, 1.04) 1.01 (0.97, 1.05) 0.97 (0.94, 0.99)
After birth     
8) Child's age at Questionnaire 1 (month) 0.97 (0.90, 1.04) 1.07 (0.97, 1.19) 1.02 (0.93, 1.13) 0.97 (0.90, 1.04)
  1. 1Odds ratio expresses risk of adverse developmental/behavioural outcome per unit increase in exposure, adjusted for centre and congenital infection status
  2. 2Odds ratio expresses risk of adverse developmental/behavioural outcome, adjusted for centre and congenital infection status
  3. 3Adverse outcome defined by score corresponding most closely to the least able/most worried 10% in the uninfected children
  4. 4Adverse outcome defined by developers of SDQ questionnaire.
  5. 5Defined by answering 'yes' or 'a little' to question(s) about concerns.