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Table 2 Factors associated with development and behaviour at 3 years, adjusted for centre and congenital infection status (Total N = 705)

From: Association between congenital toxoplasmosis and parent-reported developmental outcomes, concerns, and impairments, in 3 year old children

EXPOSURES Infection status   Odds ratio for abnormal developmental outcome (95% confidence interval)
     Parent completed   Child completed
Before birth CT+ CT- Motor Speech & language Behaviour Cognition 'Draw a Man' Line, circle, cross
1) Congenital toxoplasmosis (reference = uninfected) 178 525 1.35
(0.79, 2.30)
1.32
(0.75, 2.33)
1.10
(0.70, 1.73)
0.88
(0.37, 2.08)
0.94
(0.51, 1.74)
1.05
(0.53, 2.07)
2) Maternal age (yrs) 1*
<25 40 86 1.07
(1.02, 1.12)
0.93
(0.88, 0.99)
0.92
(0.87, 0.97)
0.97
(0.90, 1.05)
1.04
(0.99, 1.09)
1.00
(0.93, 1.07)
25–35 106 288       
>35 27 35       
3) Parity 1*
0 40 179 1.00
(0.80, 1.24)
1.18
(0.94, 1.48)
0.97
(0.74, 1.27)
1.22
(0.93, 1.60)
0.96
(0.70, 1.31)
1.02
(0.74, 1.40)
= 1 72 212       
Missing 66 136       
4) Maternal education 1
Primary 14 48 1.15
(0.89, 1.48)
0.58
(0.44, 0.77)
0.77
(0.63, 0.94)
0.74
(0.52, 1.05)
1.20
(0.87, 1.66)
1.01
(0.73, 1.38)
Secondary Lower 47 181       
Secondary Upper 47 135       
Further Education 66 152       
Missing 4 11       
5) Mother born outside country 2
Yes 25 60 1.45
(0.74, 2.84)
2.30
(1.14, 4.63)
1.65
(0.92, 2.96)
2.25
(0.88, 5.78)
0.89
(0.39, 2.01)
1.66
(0.72, 3.83)
no (reference) 152 462       
Missing 1 5       
6) Child's gender 2
Male (reference) 95 284 1.45
(0.74, 2.84)
0.81
(0.49, 1.36)
1.65
(0.92, 2.96)
2.25
(0.88, 5.78)
0.89
(0.39, 2.01)
1.66
(0.72, 3.83)
Female 83 232       
Missing 0 11       
7) Duration of prenatal treatment 1 (mean wks, sd) 6.3
(6.5)
15.1
(12.2)
1.00
(0.98, 1.02)
1.02
(0.99, 1.05)
1.00
(0.98, 1.02)
0.99
(0.96, 1.02)
0.98
(0.96, 1.01)
1.00
(0.98, 1.03)
Missing 0 0       
Exposures after birth
8) Child's age at questionnaire 1 (months) Median, IQR 38
(37,40)
39
(38, 41)
0.81
(0.71, 0.93)
0.87
(0.77, 0.98)
0.98
(0.93, 1.04)
0.73
(0.56, 0.97)
0.88
(0.80, 0.97)
0.73
(0.60, 0.88)
Missing 0 1       
  1. 1Odds ratio expresses risk of adverse developmental/behavioural outcome per unit increase in exposure, adjusted for centre and congenital infection status.
  2. 2Odds ratio expresses risk of adverse developmental/behavioural outcome, adjusted for centre and congenital infection status