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Table 4 Effect of ACE genotype on Outcomes in Caucasian Infants

From: The Angiotensin Converting Enzyme Insertion/Deletion polymorphism is not associated with an increased risk of death or bronchopulmonary dysplasia in ventilated very low birth weight infants

 

ACE Genotype

 

II (n = 11)

ID (n = 17)

DD (n = 19)

P value

Oxygen at 28 days

6/11 (55)

10/15 (67)

9/18 (47)

0.620

Oxygen at 36 weeks PCA

3/10 (30)

4/15 (27)

3/18 (17)

0.674

Death <28 days

0 (0)

1 (16)

1 (5)

0.724

Death or Oxygen at 36 weeks

4 (36)

6 (35)

4 (21)

0.558

Death ≥ 28 days

3 (27)

1 (6)

0 (0)

0.039

IVHa

2/10 (20)

6/17 (35)

1/19 (5)

0.076

IVH ≥ Grade 3a

2/10 (20)

3/17 (18)

1/19 (5)

0.415

PVLa

3/10 (30)

0/17 (0)

1/19 (5)

0.022

  1. Numbers in parenthesis represent percentages.
  2. aNot all infants had cranial US evaluations
  3. PCA Postconceptional age IVH Intraventricular Hemorrhage PVL Periventricular leukomalacia
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BMC Pediatrics

ISSN: 1471-2431

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