Total number of items | Decade | ||||
---|---|---|---|---|---|
 | 1970s (n = 5) | 1980s (n = 47) | 1990s (n = 186) | 2000s (n = 13) | Total (n = 251) |
Randomization, mean (sd) | 0.2 (0.8) | 0.7 (0.7) | 1.0 (0.6) | 1.2 (0.6) | 0.9 (0.6) |
Double-blinding, mean (sd) | 0.8 (1.1) | 0.6 (0.9) | 0.6 (0.9) | 0.6 (0.9) | 0.6 (0.9) |
Withdrawals/dropouts, n (%) | 2 (40.0) | 12 (25.5) | 89 (47.8) | 2 (15.4) | 105 (41.8) |
Overall = 5, mean (sd) | 1.4 (1.7) | 1.6 (1.3) | 2.0 (1.2) | 2.0 (1.5) | 1.9 (1.3) |
Unclear allocation concealment, n (%) | 4 (80.0) | 41 (87.2) | 150 (80.6) | 9 (69.2) | 204 (81.3) |