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Table 3 Association between femur shaft fractures and injury requiring hospital admission grouped according to follow-up time after injury among 1,404 children (exposed) who were one to three years of age when they suffered a femur shaft fracture with the risk among 13,814 (unexposed) randomly selected, gender- and age-matched femur fracture–free children

From: Femur shaft fracture at a young age and the risk of subsequent severe injuries during childhood: a cohort study

 

Regardless of follow-up time

Follow-up, up to three years

Follow-up, more than three years

P-valuea

 

Number of events exposed

Number of events unexposed

HRb(CI)

Number of events exposed

Number of events unexposed

HRb(CI)

Number of events exposed

Number of events unexposed

HRb(CI)

 

All injuriesc

97

885

1.08 (0.88–1.33)

23

241

0.94 (0.61–1.44)

74

644

1.13 (0.89–1.44)

0.45

Boys

83

717

1.14 (0.91–1.43)

22

199

1.09 (0.70–1.69)

61

518

1.16 (0.89–1.51)

0.80

Girls

14

168

0.91 (0.42–1.98)

1

42

0.23 (0.03-1.69)

13

126

1.02 (0.57–1.80)

0.16

All fractures

54

388

1.38 (1.04–1.84)

10

73

1.35 (0.70–2.62)

44

315

1.39 (1.01–1.90)

0.94

Boys

47

312

1.50 (1.10–2.03)

10

57

1.73 (0.88–3.38)

37

255

1.44 (1.02–2.04)

0.64

Girls

7

76

0.91 (0.42–1.98)

0

16

N.A.

7

60

1.15 (0.53–2.52)

0.98

Upper-limb fracturesd

33

297

1.09 (0.76–1.57)

5

53

0.93 (0.37–2.32)

28

244

1.13 (0.76–1.67)

0.70

Boys

29

239

1.19 (0.81–1.75)

5

42

1.17 (0.46–2.95)

24

197

1.20 (0.79–1.83)

0.96

Girls

4

58

0.68 (0.25–1.86)

0

11

N.A.

4

47

0.83 (0.30–2.31)

0.98

Lower-limb fracturesd, e

17

68

2.49 (1.46–4.23)

5

15

3.27 (1.19–9.00)

12

53

2.26 (1.21–4.23)

0.54

Boys

14

53

2.62 (1.45–4.71)

5

10

4.90 (1.67–14.33)

9

43

2.08 (1.01–4.26)

0.19

Girls

3

15

2.02 (0.58–6.97)

0

5

N.A.

3

10

3.05 (0.84–11.10)

0.99

Soft-tissue injury

46

562

0.80 (0.59–1.08)

13

171

0.74 (0.43–1.31)

33

391

0.83 (0.58–1.18)

0.77

Boys

38

457

0.81 (0.58–1.13)

12

145

0.81 (0.45–1.47)

26

312

0.81 (0.54–1.21)

0.99

Girls

8

105

0.76 (0.37–1.55)

1

26

0.38 (0.05–2.77)

7

79

0.89 (0.41–1.92)

0.43

  1. aP-value for difference between HR up to three years and HR more than three years. bAdjusted by matching for year of fracture and corresponding date for unexposed, age, and sex. cInjuries resulting in a fracture or soft-tissue injury requiring hospital admission. dSome children had experienced both upper- and lower-limb fractures. eExcept for femur fractures (regardless of localization). Significant values are written in bold type.