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Table 1 First detection of specific autoantibodies compared to the age of onset of APS 1 components

From: Cutaneous vasculitis in patients with autoimmune polyendocrine syndrome type 1: report of a case and brief review of the literature

Specific autoantibodies Age at first test (years) Age at first detection (years) Related APS 1 component Onset of APS 1 component (years)
Anti-thyroglobulin 5 5 Autoimmune thyroiditis 5
Anti-thyreoperoxidase 5 5 Autoimmune thyroiditis 5
Anti-parietal cells 7 7 Autoimmune gastritis -
Anti-adrenal cortex 7 7 Addison disease 11
Anti-21-hydroxylase 8 8 Addison disease 11
Anti-17alpha hydroxylase 8 8 Addison disease 11
Ovarian failure 12
Anti-P450 side chain cleavage 8 8 Addison disease 11
Ovarian failure 12
Anti-steroid-producing cells 8 8 Ovarian failure 12
Anti-tryptophan hydroxylase 9 10 Autoimmune hepatitis -
Autoimmune enteropathy 5
Anti-L-aminoacid decarboxylase 9 10 Vitiligo 9
Autoimmune hepatitis -