Total (n = 90) | Non-IVH (n = 73) | IVH (n = 17) | p-value | |
---|---|---|---|---|
Gestational age [weeks + days] | 28 + 0 (23 + 3 -31 + 5) | 28 + 3 (24 + 0 - 31 + 5) | 27 + 0 (23 + 3 - 30 + 2) | 0.016 |
Birth weight [g] | 990 (320 – 2270) | 990 (400 – 2270) | 920 (320 – 1495) | 0.248 |
Male [%] | 67.8 | 67.1 | 70.6 | 1.000 |
SGA [%] | 18.9 | 19.2 | 17.6 | 0.727 |
Prenatal steroids [%] | 67.4 | 68.1 | 64.7 | 0.781 |
AIS [%] | 5.6 | 5.5 | 5.9 | 1.000 |
Cesarean section [%] | 98.9 | 98.6 | 100 | 1.000 |
Surfactant [%] | 83.3 | 79.5 | 100 | 0.065 |
RDS [%] | 85.6 | 84.9 | 88.2 | 1.000 |
RDS [median grade] | 2 | 2 | 2 | 0.549 |
CPAP [%] | 88.9 | 93.2 | 70.6 | 0.019 |
Intubation [%] | 41.1 | 34.2 | 70.6 | 0.012 |
PDA [%] | 75.6 | 71.2 | 94.1 | 0.061 |
PDA medicament [%] | 78.9 | 75.3 | 94.1 | 0.108 |
PDA OP [%] | 5.6 | 2.7 | 17.6 | 0.045 |
Sepsis [%] | 10.0 | 6.8 | 23.5 | 0.061 |
Catecholamines [%] | 42.2 | 38.4 | 58.8 | 0.173 |
umbilical artery pH | 7.33 (7.15 - 7.52) | 7.33 (7.15 - 7.52) | 7.34 (7.22 - 7.38) | 0.530 |
Apgar 5 min | 8 (2–10) | 8 (2–10) | 8 (6–9) | 0.183 |
CRIB-Score | 2.5 (0–16) | 2.0 (0–14) | 5.0 (1–16) | 0.495 |
Mean arterial pressure [mmHg] | 33.5 (19–60) | 34.0 (20–60) | 27 (19–42) | 0.053 |
Hematocrit [%] | 45.0 (10.7 - 59.0) | 47.0 (10.7 - 59.0) | 41.0 (24.0 - 59.0) | 0.075 |
Leucocytes [×103/μl] | 7.24 (1.08 - 32.00) | 7.39 (1.08 - 32.00) | 6.63 (1.16 - 26.25) | 0.613 |
Thrombocytes [×103/μl] | 160 (15–291) | 150 (15–272) | 175 (30–291) | 0.270 |
Il-6 [pg/ml] | 51.6 (2.0 - 689,002.0) | 42.3 (2.0 - 57,050.0) | 92.1 (12.9 - 689,002.0) | 0.197 |
CRP [mg/l] | 0.2 (0.2 - 78.2) | 0.2 (0.2 - 78.2) | 0.2 (0.2 – 20.9) | 0.461 |
FII [activity in%] | 32 (17–65) | 35 (17–65) | 27 (18–36) | 0.001/*0.006 |
FVII [activity in%] | 31 (7–93) | 31,5 (7–93) | 29 (10–48) | 0.116/*0.281 |
FX [activity in%] | 41 (14–89) | 46 (14–89) | 33 (24–62) | 0.007/*0.023 |
ATIII [activity in%] | 30 (13–51) | 30.0 (13–51) | 28 (13–45) | 0.241/*0.383 |