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Table 2 Meta-analysis summary estimates of breast milk composition per 100 milliliters at various postnatal ages (mean (+/−2 standard deviations))

From: A systematic review and meta-analysis of the nutrient content of preterm and term breast milk

Preterm

Energy (kcal)

Protein (g)

Fat (g)

Calcium (mg)

Phosphorus (mg)

1st week

60 (45–75)

2.2 (0.3-4.1)

2.6 (0.5-4.7)

26 (9–43)

11 (1–22)

2nd week

71 (49–94)

1.5 (0.8-2.3)

3.5 (1.2-5.7)

25 (11–39)

15 (8–21)

Week 3/4

77 (61–92)

1.4 (0.6-2.2)

3.5 (1.6-5.5)

25 (13–36)

14 (8–20)

Week 10/12

66 (39–94)

1.0 (0.6-1.4)

3.7 (0.8-6.5)

29 (19–38)

12 (8–15)

Term

Energy (kcal)

Protein (g)

Fat (g)

Calcium (mg)

Phosphorus (mg)

1st week

60 (44–77)

1.8 (0.4-3.2)

2.2 (0.7-3.7)

26 (16–36)

12 (6–18)

2nd week

67 (47–86)

1.3 (0.8-1.8)

3.0 (1.2-4.8)

28 (14–42)

17 (8–27)

Week 3/4

66 (48–85)

1.2 (0.8-1.6)

3.3 (1.6-5.1)

27 (18–36)

16 (10–22)

Week 10/12

68 (50–86)

0.9 (0.6-1.2)

3.4 (1.6-5.2)

26 (14–38)

16 (9–22)

  1. Estimates as +/− 2 standard deviations assumed no skew. Energy values were bomb calorimeter measured values except for 10–12 weeks, which were calculated values. Protein values are true measured protein, not based on total nitrogen content.