Otitis media in children vaccinated during consecutive 7-valent or 10-valent pneumococcal conjugate vaccination schedules

Table 7 Univariate and multivariate analyses of risk factors for suppurative OM, adjusted for community

	With suppurative OM**	UNI-VARIATE OR	95% CI	p	MULTI-VARIATE OR	95% CI	P*
Vaccine group
PCV7	51%
PHiD-CV10	39%	0.64	0.48 to 0.86	0.003	0.58	0.41 to 0.80	0.001
Children under age of 5 years in household
0	39%			0.003			0.009
1	47%	1.43	0.98 to 2.10		1.34	0.91 to 1.98
2	53%	1.85	1.12 to 3.07		1.66	0.99 to 2.80
3+	60%	2.42	1.46 to 3.99		2.36	1.41 to 4.00
Age group (years)
< 1 year	58%			0.000			0.000
1 to < 2 years	47%	0.70	0.49 to 1.0		0.72	0.50 to 1.04
2 to < 3 years	30%	0.33	0.22 to 0.49		0.31	0.20 to 0.47
Gender
Male	41%
Female	49%	1.41	1.07 to 1.86	0.016	1.46	1.07 to 1.92	0.016
Antibiotics prescribed in previous 5 weeks
None	44%
Any	47%	1.21	0.90 to 1.62	0.20	1.24	0.91 to 1.69	0.17
Haemoglobin
> = 11 mg/dL	42%
<11 mg/dL	49%	1.28	0.93 to 1.75	0.13
Child care attendance
none	47%
any	47%	1.03	0.64 to 1.67	0.91
Sibling history of OM “runny ears’
No	47%
Yes	47%	0.98	0.69 to 1.39	0.90
Maternal smoking
No	46%
Yes	48%	1.11	0.80 to 1.53	0.53
Child near campfire last week
No	48%
Yes	47%	0.89	0.63 to 1.35	0.51
Maternal age at birth of this child
> = 21 yrs	43%
< 21 yrs	52%	1.39	0.97 to 1.99	0.07
Maternal education
no certificate	46%
certificate	49%	1.07	0.74 to 1.57	0.71
Breastfed
Never	51%
Some	47%	0.86	0.45 to 1.65	0.65
Pacifier
Never	47%
Some	47%	1.02	0.70 to 1.54	0.91
Gestational age
> = 32 weeks	45%
< 32 weeks	54%	1.3	0.60 to 3.06	0.51

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