Table 3 Participant characteristics, general health and antibiotics prescribed, by vaccination group
PCV7 | PHiD-CV1 | Absolute difference in mean or % [95% CI] | P* | |||
|---|---|---|---|---|---|---|
N | Mean (SD) or% | N | Mean (SD) or% | |||
Age (mo) | 444 | 20 (8) | 451 | 18 (7) | 2 [1-3] | 0.0001 |
0 to <3 | 0 | 0 | ||||
3 to <6 | 8 | 2% | 9 | 2% | ||
6 to <9 | 48 | 11% | 60 | 13% | ||
9 to <12 | 39 | 9% | 46 | 10% | ||
12 to <18 | 87 | 20% | 118 | 26% | ||
18 to <24 | 102 | 23% | 106 | 24% | ||
24 to <36 | 160 | 36% | 112 | 25% | ||
Gestational age (weeks) | 378 | 37.7 (2.8) | 426 | 38.1 (2.3) | 0.4 [0 to 0.7] | 0.04 |
Birth weight (kg) | 431 | 2.97 (0.65) | 431 | 3.06 (0.61) | 0.09 [0.00 to 0.17] | 0.04 |
Sex (female) | 210 | 47% | 230 | 51% | 4% [−3 to 10] | 0.27 |
General health | ||||||
SKIN assessed | 434/444 | 98% | 435/451 | 96% | ||
Normal | 326 | 75% | 303 | 70% | −5% [−11 to 0] | 0.07 |
Scabies | 19 | 4% | 53 | 12% | 8% [−4 to 11] | <0.0001 |
Impetigo | 62 | 14% | 67 | 15% | 1% [−4 to 6] | 0.64 |
Tinea | 19 | 2% | 13 | 3% | 1% [−1 to 3] | 0.39 |
other | 20 | 6% | 27 | 6% | 0% [−3 to 3] | 0.96 |
Runny Nose | 165/432 | 38% | 198/445 | 44% | 6% [0 to 13] | 0.06 |
Any cough | 86/436 | 20% | 169/457 | 38% | 18% [12 to 24] | <0.0001 |
Other | ||||||
Any antibiotics prescribed in previous 5 weeks | 130/444 | 29% | 189/451 | 42% | 12% [6 to 19] | 0.0001 |
Beta-lactam | 101/444 | 23% | 158 | 35% | 12% [6-18] | 0.0001 |
Macrolide | 14/444 | 3% | 18 | 4% | 1% [−2 to 3] | 0.50 |
Topical | 18/426 | 4% | 18/433 | 4% | 0% [−3 to 3] | 0.97 |
Haemoglobin (<11 mg/dL) | 122/402 | 30% | 139/403 | 34% | 4% [−2 to 11] | 0.21 |