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Table 3 Participant characteristics, general health and antibiotics prescribed, by vaccination group

From: Otitis media in children vaccinated during consecutive 7-valent or 10-valent pneumococcal conjugate vaccination schedules

  PCV7 PHiD-CV1 Absolute difference in mean or % [95% CI] P*
  N Mean (SD) or% N Mean (SD) or%   
Age (mo) 444 20 (8) 451 18 (7) 2 [1-3] 0.0001
0 to <3 0   0    
3 to <6 8 2% 9 2%   
6 to <9 48 11% 60 13%   
9 to <12 39 9% 46 10%   
12 to <18 87 20% 118 26%   
18 to <24 102 23% 106 24%   
24 to <36 160 36% 112 25%   
Gestational age (weeks) 378 37.7 (2.8) 426 38.1 (2.3) 0.4 [0 to 0.7] 0.04
Birth weight (kg) 431 2.97 (0.65) 431 3.06 (0.61) 0.09 [0.00 to 0.17] 0.04
Sex (female) 210 47% 230 51% 4% [−3 to 10] 0.27
General health
SKIN assessed 434/444 98% 435/451 96%   
Normal 326 75% 303 70% −5% [−11 to 0] 0.07
Scabies 19 4% 53 12% 8% [−4 to 11] <0.0001
Impetigo 62 14% 67 15% 1% [−4 to 6] 0.64
Tinea 19 2% 13 3% 1% [−1 to 3] 0.39
other 20 6% 27 6% 0% [−3 to 3] 0.96
Runny Nose 165/432 38% 198/445 44% 6% [0 to 13] 0.06
Any cough 86/436 20% 169/457 38% 18% [12 to 24] <0.0001
Other
Any antibiotics prescribed in previous 5 weeks 130/444 29% 189/451 42% 12% [6 to 19] 0.0001
Beta-lactam 101/444 23% 158 35% 12% [6-18] 0.0001
Macrolide 14/444 3% 18 4% 1% [−2 to 3] 0.50
Topical 18/426 4% 18/433 4% 0% [−3 to 3] 0.97
Haemoglobin (<11 mg/dL) 122/402 30% 139/403 34% 4% [−2 to 11] 0.21
  1. *Bold signifies P value less than 0.05.