Table 2 Distribution of systemic antibiotic subgroupsa by age group in 2008 (children and adolescents ≤18 years)
| Â | Aarhus (DK) | Emilia Romagna (IT) | GePaRD (DE) | PHARMO (NL) | THIN (UK) | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|  | ≤ 4 | 5-9 | 10-14 | 15-18 | 0-18 | ≤ 4 | 5-9 | 10-14 | 15-18 | 0-18 | ≤ 4 | 5-9 | 10-14 | 15-18 | 0-18 | ≤ 4 | 5-9 | 10-14 | 15-18 | 0-18 | ≤ 4 | 5-9 | 10-14 | 15-18 | 0-18 |
Tetracyclines | - | - | 0.3 | 1.7 | 0.4 | <0.1 | <0.1 | 1.1 | 4.1 | 0.6 | <0.1 | 0.1 | 3.8 | 11.7 | 3.3 | <0.1 | 0.1 | 9.6 | 24.2 | 6.7 | <0.1 | <0.1 | 8.6 | 26.3 | 7.8 |
Broad spectrum penicillins | 47.8 | 24.2 | 12.7 | 14.8 | 31.0 | 62.4 | 57.5 | 51.3 | 44.0 | 57.4 | 28.4 | 23.5 | 23.3 | 17.5 | 23.8 | 73.3 | 60.3 | 43.0 | 21.8 | 54.9 | 62.0 | 47.3 | 34.7 | 20.8 | 44.2 |
Narrow spectrum penicillins | 42.6 | 63.8 | 69.4 | 48.5 | 51.7 | <0.1 | 0.1 | 0.2 | 0.2 | 0.1 | 11.7 | 19.8 | 15.4 | 12.7 | 14.8 | 4.9 | 9.7 | 13.7 | 12.7 | 8.9 | 16.0 | 28.1 | 31.8 | 25.1 | 23.5 |
Second generation cephalosporins | <0.1 | <0.1 | <0.1 | <0.1 | <0.1 | 5.1 | 4.7 | 3.0 | 2.0 | 4.3 | 27.5 | 21.1 | 15.6 | 8.7 | 19.4 | 0.1 | 0.3 | 0.1 | 0.1 | 0.2 | 1.2 | 1.1 | 0.8 | 0.4 | 0.9 |
Third generation cephalosporins | - | - | - | <0.1 | <0.1 | 14.7 | 14.8 | 13.9 | 10.6 | 14.1 | 8.8 | 5.9 | 5.2 | 3.8 | 6.3 | <0.1 | <0.1 | 0.1 | 0.2 | 0.1 | 0.1 | 0.1 | 0.1 | <0.1 | 0.1 |
Sulfonamides/trimethoprim | 0.9 | 2.8 | 3.5 | 9.5 | 3.6 | 0.4 | 0.5 | 0.7 | 1.0 | 0.5 | 3.8 | 5.4 | 5.5 | 7.8 | 5.4 | 5.3 | 7.1 | 6.3 | 6.5 | 6.1 | 4.9 | 6.4 | 5.2 | 7.7 | 5.9 |
Macrolides | 8.3 | 7.6 | 13.0 | 24.7 | 12.5 | 16.7 | 21.0 | 27.2 | 28.9 | 20.7 | 16.7 | 18.8 | 24.9 | 23.5 | 20.3 | 15.2 | 17.4 | 18.7 | 14.2 | 16.0 | 12.2 | 11.7 | 13.7 | 12.6 | 12.5 |
Nitrofuran derivatives | 0.1 | 1.4 | 0.8 | 0.7 | 0.6 | <0.1 | <0.1 | <0.1 | <0.1 | <0.1 | 0.2 | 0.6 | 0.4 | 0.4 | 0.4 | 0.7 | 4.3 | 6.9 | 16.3 | 5.8 | 0.2 | 0.5 | 0.4 | 0.8 | 0.4 |
Others | 0.2 | 0.2 | 0.3 | 0.3 | 0.2 | 0.6 | 1.4 | 2.8 | 9.1 | 2.1 | 2.8 | 4.7 | 5.9 | 13.9 | 6.3 | 0.5 | 0.9 | 1.8 | 3.9 | 1.4 | 3.4 | 4.8 | 4.7 | 6.3 | 4.6 |