Haemophilus influenzae type b as an important cause of culture-positive acute otitis media in young children in Thailand: a tympanocentesis-based, multi-center, cross-sectional study

Table 3 Antibacterial non-susceptibility of S. pneumoniae and H. influenzae isolates

	Number of non-susceptible¹isolates
Antibiotic	S. pneumoniae isolates (N = 27)²	H. influenzae isolates (N = 21)
Amoxicillin/Clavulanate	0 (0%)	0 (0%)
Ampicillin³	-	4 (20%)
Azithromycin	26 (96%)	2 (10%)
Cefotaxime	3 (11%)	0 (0%)
Cefuroxime	17 (63%)	1 (5%)
Chloramphenicol	7 (26%)	2 (10%)
Erythromycin⁴	18 (67%)	-
Levofloxacin	0 (0%)	0 (0%)
Penicillin⁴	0 (0%)	-
Tetracycline	18 (67%)	2 (10%)
Trimethoprim/Sulfamethoxazole	21 (78%)	7 (33%)

¹Intermediate or resistant based on the Clinical and Laboratory Standards Institute 2009 standards.
²Two isolates are coming from the same child with a bilateral infection.
³Ampicillin resistance data missing for one H. influenzae isolate. Ampicillin sensitivity was not performed for S. pneumoniae.
⁴For H. influenzae, the median value of MIC was equal to 4.0 for Erythromycin and 0.250 for Penicillin.

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