Table 3 Post-surfactant characteristics for 322 neonates born prior to 32 weeks gestation, 1998–2010

CRIB-score, median (IQR)³

2 (1–2)

2 (2–6)*

2 (2–5)*

6 (2–8)*

CRIB-score > 4, n (%)³

6 (8)

9 (32)*

9 (36)*

79 (66)*

Given < 6 hours after surfactant:

 Inotropes, n (%)²

2 (2)

5 (15)*

1 (3)

56 (35)*

 Packed red blood cells, n (%)²

6 (6)

3 (9)

1 (3)

18 (11)

 Volume expansion, n (%)²

10 (10)

5 (15)

5 (16)

72 (46)*

Antibiotics ≥ 7 days, n (%)²

17 (17)

6 (18)

12 (39)*

61 (39)*

Pneumothorax²

2 (2)

8 (25)*

1 (3)

35 (23)*

Necrotizing enterocolitis, n (%)²

10 (10)

8 (24)*

4 (13)

56 (36)*

 Clinical suspicion or x-ray changes

9

5

4

50

 Surgery

1

3

0

6

Patent ductus arteriosus on first echocardiography, n (%)²

33 (33)

16 (48)

13 (42)

71 (45)

 No treatment

19

11

11

49

 NSAID/surgery

14

5

2

22

Intraventricular hemorrhage, n (%)²

38 (38)

12 (36)

7 (23)

73 (46)

 Grades I–II

34

7

3

32

 Grades III–IV

4

5

4

41

Periventricular leukomalasia, n (%)²

4 (4)

1 (3)

2 (6)

15 (9)

BPD, n (%)^1,4

12 (18)

5 (26)

4 (24)

27 (46)*

Retinopathy of prematurity grade III, n (%)²

3 (3)

1 (3)

0 (0)

12 (8)

MV days, median (IQR)²

0.01 (0.00–0.03)

3.26 (1.59–4.45)*

0.70 (0.33–0.92)*

3.26 (1.77–6.98)*

CPAP days, median (IQR)²

17.5 (9.3–31.5)

21.5 (10.3–33.1)

19.0 (6.7–34.1)

22.4 (1.2–36.2)

Oxygen days, median (IQR)²

6 (2–20)

10 (4–29)

5 (0–21)

15 (3–40)*

Neonatal death < 28 days, n (%)²

1 (1)

4 (12)*

2 (6)

41 (26)*