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Table 3 Summary of logistic regression analyses of atopic diseases in late childhood in 586 Norwegian children according to mother’s preeclampsia status

From: Birth after preeclamptic pregnancies: association with allergic sensitization and allergic rhinoconjunctivitis in late childhood; a historically matched cohort study

Effects of maternal preeclampsia
  Fully adjusteda) Final analysisb)
  n Mild/moderate preeclampsia Severe preeclampsia Likelihood-ratio- n Mild/moderate preeclampsia Severe preeclampsia Likelihood-ratio
Outcome variable   OR 95% CI OR 95% CI p   OR 95% CI OR 95% CI p
FU1 variables             
Allergic rhinoconjunctivitis 514 1.21 (0.70, 2.07) 2.10 (0.86, 5.11) 0.268 586 1.25 (0.79, 1.97) 2.23 (1.20, 4.17) 0.046
Atopic dermatitis 513 0.90 (0.54, 1.50) 0.97 (0.39, 2.39) 0.914       ____
Asthma 506 0.87 (0.38, 1.97) 0.72 (0.19, 2.77) 0.878       ____
FU2 variables             
Allergic sensitization 329 1.49 (0.84, 2.63) 2.44 (0.93, 6.42) 0.138       ____
High level allergic sensitizationc) 329 1.64 (0.87, 3.11) 4.42 (1.58, 12.3) 0.015 347 1.60 (0.88, 2.91) 4.05 (1.62, 10.1) 0.010d)
Current asthma 388 1.11 (0.45, 2.73) 0.69 (0.15, 3.18) 0.802       ____
  1. Abbreviations: OR Odds ratio, CI Confidence interval, FU1 first follow-up at the ages of 10.8 years (girls) and 11.8 years (boys), FU2 second follow-up at the age of 12.8 years (both genders); Likelihood-ratio-p refers to exposure only.
  2. a)Adjusted for gender, birth weight z-score adjusted for gestational age, being firstborn, Caesarean section, maternal smoking during pregnancy, gestational age in weeks, maternal age, maternal body mass index (kg/m2) and maternal asthma;
  3. b)After backward stepwise selection from fully adjusted model with p ≤ 0.05; all final analyses include the covariates gender and maternal asthma as default.
  4. c)High level allergic sensitization = Sum of specific IgE > 3.9 kU/l; the 25 percentile of sensitized children.
  5. d)Adjusted for gender, maternal smoking during pregnancy, gestational age in weeks and maternal asthma. No significant interaction effects were found in final analyses.