Skip to main content

Table 3 Recurrent wheezing during study period

From: Persistent recurring wheezing in the fifth year of life after laboratory-confirmed, medically attended respiratory syncytial virus infection in infancy

   RW 2nd Year RW 3rd Year RW 4th Year RW 5th Year RW 2nd–5th Years
  N n % n % n % n % n %
All children 72,602 4,091 5.6 3,492 4.8 3,466 4.8 3,380 4.7 9,151 12.6
Sex            
 Female 35,606 1,402 3.9 1,261 3.5 1,318 3.7 1,330 3.7 3,499 9.8
 Male 36,996 2,689 7.3 2,231 6.0 2,148 5.8 2,050 5.5 5,652 15.3
Race*            
 White 31,580 1,650 5.2 1,443 4.6 1,353 4.3 1,265 4.0 3,642 11.5
 African-American 6,454 517 8.0 409 6.3 420 6.5 441 6.8 1,093 16.9
 Asian 14,476 807 5.6 774 5.3 785 5.4 764 5.3 1,983 13.7
 Hispanic 15,189 876 5.8 644 4.2 670 4.4 664 4.4 1841 12.1
 Other/unknown 4,903 241 4.9 222 4.5 238 4.9 246 5.0 592 12.1
Maternal age, y            
 <18 911 55 6.0 38 4.2 37 4.1 44 4.8 118 13.0
 18–34 53,125 3,068 5.8 2,530 4.8 2,571 4.8 2,453 4.6 6,779 12.8
 ≥35 18,566 968 5.2 924 5.0 858 4.6 883 4.8 2,254 12.1
Family history of asthma*            
 None 68,824 3,698 5.4 3,131 4.5 3,135 4.6 3,053 4.4 8,320 12.1
 Father only 1,087 91 8.4 94 8.6 92 8.5 83 7.6 220 20.2
 Mother only 2,633 294 11.2 258 9.8 232 8.8 240 9.1 596 22.6
 Both parents 58 8 13.8 9 15.5 7 12.1 4 6.9 15 25.9
Sibling aged <5 y in home            
 None 44,590 2,358 5.3 2,127 4.8 2,246 5.0 2,197 4.9 5,631 12.6
 ≥1 28,012 1,733 6.2 1,365 4.9 1,220 4.4 1,183 4.2 3,520 12.6
Congenital anomaly*            
 Absent 67,605 3,739 5.5 3,176 4.7 3,170 4.7 3,079 4.6 8,371 12.4
 Present 4,997 352 7.0 316 6.3 296 5.9 301 6.0 780 15.6
Small for gestational age*            
 No 71,582 4,011 5.6 3,424 4.8 3,405 4.8 3,328 4.6 8,989 12.6
 Yes 1020 80 7.8 68 6.7 61 6.0 52 5.1 162 15.9
Gestational age, wk*            
 32–33 936 99 10.6 81 8.7 78 8.3 75 8.0 188 20.1
 34-36 4,665 401 8.6 290 6.2 294 6.3 294 6.3 793 17.0
 37 4,582 270 5.9 264 5.8 209 4.6 238 5.2 635 13.9
 38–40 51,049 2,763 5.4 2,373 4.6 2,345 4.6 2,290 4.5 6,235 12.2
 ≥41 11,370 558 4.9 484 4.3 540 4.7 483 4.2 1,300 11.4
Oxygen exposure* and BPD*            
 No oxygen, no BPD 6,9821 3,819 5.5 3,267 4.7 3,249 4.7 3,162 4.5 8,607 12.3
 <200 h Oxygen, no BPD 2,431 221 9.1 177 7.3 165 6.8 173 7.1 445 18.3
 ≥200 h Oxygen, no BPD 300 43 14.3 34 11.3 45 15.0 36 12.0 80 26.7
 BPD 50 8 16.0 14 28.0 7 14.0 9 18.0 19 38.0
Unspecified respiratory hospitalization*            
 None 72,345 4017 5.6 3,449 4.8 3,420 4.7 3,348 4.6 9,052 12.5
 Uncomplicated hospitalization 177 47 26.6 24 13.6 26 14.7 16 9.0 64 36.2
 Prolonged hospitalization 80 27 33.8 19 23.8 20 25.0 16 20.0 35 43.8
Laboratory-confirmed, medically attended RSV infection*            
 None 71,336 3,829 5.4 3,326 4.7 3,312 4.6 3,280 4.6 8,748 12.3
 Outpatient 762 127 16.7 79 10.4 74 9.7 50 6.6 201 26.4
 Uncomplicated hospitalization 384 105 27.3 67 17.4 57 14.8 35 9.1 154 40.1
 Prolonged hospitalization 120 30 25.0 20 16.7 23 19.2 15 12.5 48 40.0
Laboratory-confirmed, medically attended infection with other pathogen*            
 None 72,382 4,056 5.6 3,476 4.8 3,449 4.8 3,362 4.6 9,101 12.6
 Outpatient 119 20 16.8 7 5.9 7 5.9 8 6.7 30 25.2
 Uncomplicated hospitalization 64 7 10.9 3 4.7 5 7.8 5 7.8 10 15.6
 Prolonged hospitalization 37 8 21.6 6 16.2 5 13.5 5 13.5 10 27.0
Definite, medically attended RSV encounter in the first year of life*            
 No 71,336 3,829 5.4 3,326 4.7 3,312 4.6 3,280 4.6 8,748 12.3
 Yes 1,266 262 20.7 166 13.1 154 12.2 100 7.9 403 31.8
  1. Abbreviations: BPD Bronchopulmonary dysplasia, RSV  Respiratory syncytial virus, RW Recurrent wheezing, wk weeks, y years.
  2. *Please refer to the appropriate section of the footnotes to Table 1 for further details.