Table 3 Recurrent wheezing during study period
RW 2nd Year | RW 3rd Year | RW 4th Year | RW 5th Year | RW 2nd–5th Years | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
N | n | % | n | % | n | % | n | % | n | % | |
All children | 72,602 | 4,091 | 5.6 | 3,492 | 4.8 | 3,466 | 4.8 | 3,380 | 4.7 | 9,151 | 12.6 |
Sex | |||||||||||
Female | 35,606 | 1,402 | 3.9 | 1,261 | 3.5 | 1,318 | 3.7 | 1,330 | 3.7 | 3,499 | 9.8 |
Male | 36,996 | 2,689 | 7.3 | 2,231 | 6.0 | 2,148 | 5.8 | 2,050 | 5.5 | 5,652 | 15.3 |
Race* | |||||||||||
White | 31,580 | 1,650 | 5.2 | 1,443 | 4.6 | 1,353 | 4.3 | 1,265 | 4.0 | 3,642 | 11.5 |
African-American | 6,454 | 517 | 8.0 | 409 | 6.3 | 420 | 6.5 | 441 | 6.8 | 1,093 | 16.9 |
Asian | 14,476 | 807 | 5.6 | 774 | 5.3 | 785 | 5.4 | 764 | 5.3 | 1,983 | 13.7 |
Hispanic | 15,189 | 876 | 5.8 | 644 | 4.2 | 670 | 4.4 | 664 | 4.4 | 1841 | 12.1 |
Other/unknown | 4,903 | 241 | 4.9 | 222 | 4.5 | 238 | 4.9 | 246 | 5.0 | 592 | 12.1 |
Maternal age, y | |||||||||||
<18 | 911 | 55 | 6.0 | 38 | 4.2 | 37 | 4.1 | 44 | 4.8 | 118 | 13.0 |
18–34 | 53,125 | 3,068 | 5.8 | 2,530 | 4.8 | 2,571 | 4.8 | 2,453 | 4.6 | 6,779 | 12.8 |
≥35 | 18,566 | 968 | 5.2 | 924 | 5.0 | 858 | 4.6 | 883 | 4.8 | 2,254 | 12.1 |
Family history of asthma* | |||||||||||
None | 68,824 | 3,698 | 5.4 | 3,131 | 4.5 | 3,135 | 4.6 | 3,053 | 4.4 | 8,320 | 12.1 |
Father only | 1,087 | 91 | 8.4 | 94 | 8.6 | 92 | 8.5 | 83 | 7.6 | 220 | 20.2 |
Mother only | 2,633 | 294 | 11.2 | 258 | 9.8 | 232 | 8.8 | 240 | 9.1 | 596 | 22.6 |
Both parents | 58 | 8 | 13.8 | 9 | 15.5 | 7 | 12.1 | 4 | 6.9 | 15 | 25.9 |
Sibling aged <5 y in home | |||||||||||
None | 44,590 | 2,358 | 5.3 | 2,127 | 4.8 | 2,246 | 5.0 | 2,197 | 4.9 | 5,631 | 12.6 |
≥1 | 28,012 | 1,733 | 6.2 | 1,365 | 4.9 | 1,220 | 4.4 | 1,183 | 4.2 | 3,520 | 12.6 |
Congenital anomaly* | |||||||||||
Absent | 67,605 | 3,739 | 5.5 | 3,176 | 4.7 | 3,170 | 4.7 | 3,079 | 4.6 | 8,371 | 12.4 |
Present | 4,997 | 352 | 7.0 | 316 | 6.3 | 296 | 5.9 | 301 | 6.0 | 780 | 15.6 |
Small for gestational age* | |||||||||||
No | 71,582 | 4,011 | 5.6 | 3,424 | 4.8 | 3,405 | 4.8 | 3,328 | 4.6 | 8,989 | 12.6 |
Yes | 1020 | 80 | 7.8 | 68 | 6.7 | 61 | 6.0 | 52 | 5.1 | 162 | 15.9 |
Gestational age, wk* | |||||||||||
32–33 | 936 | 99 | 10.6 | 81 | 8.7 | 78 | 8.3 | 75 | 8.0 | 188 | 20.1 |
34-36 | 4,665 | 401 | 8.6 | 290 | 6.2 | 294 | 6.3 | 294 | 6.3 | 793 | 17.0 |
37 | 4,582 | 270 | 5.9 | 264 | 5.8 | 209 | 4.6 | 238 | 5.2 | 635 | 13.9 |
38–40 | 51,049 | 2,763 | 5.4 | 2,373 | 4.6 | 2,345 | 4.6 | 2,290 | 4.5 | 6,235 | 12.2 |
≥41 | 11,370 | 558 | 4.9 | 484 | 4.3 | 540 | 4.7 | 483 | 4.2 | 1,300 | 11.4 |
Oxygen exposure* and BPD* | |||||||||||
No oxygen, no BPD | 6,9821 | 3,819 | 5.5 | 3,267 | 4.7 | 3,249 | 4.7 | 3,162 | 4.5 | 8,607 | 12.3 |
<200 h Oxygen, no BPD | 2,431 | 221 | 9.1 | 177 | 7.3 | 165 | 6.8 | 173 | 7.1 | 445 | 18.3 |
≥200 h Oxygen, no BPD | 300 | 43 | 14.3 | 34 | 11.3 | 45 | 15.0 | 36 | 12.0 | 80 | 26.7 |
BPD | 50 | 8 | 16.0 | 14 | 28.0 | 7 | 14.0 | 9 | 18.0 | 19 | 38.0 |
Unspecified respiratory hospitalization* | |||||||||||
None | 72,345 | 4017 | 5.6 | 3,449 | 4.8 | 3,420 | 4.7 | 3,348 | 4.6 | 9,052 | 12.5 |
Uncomplicated hospitalization | 177 | 47 | 26.6 | 24 | 13.6 | 26 | 14.7 | 16 | 9.0 | 64 | 36.2 |
Prolonged hospitalization | 80 | 27 | 33.8 | 19 | 23.8 | 20 | 25.0 | 16 | 20.0 | 35 | 43.8 |
Laboratory-confirmed, medically attended RSV infection* | |||||||||||
None | 71,336 | 3,829 | 5.4 | 3,326 | 4.7 | 3,312 | 4.6 | 3,280 | 4.6 | 8,748 | 12.3 |
Outpatient | 762 | 127 | 16.7 | 79 | 10.4 | 74 | 9.7 | 50 | 6.6 | 201 | 26.4 |
Uncomplicated hospitalization | 384 | 105 | 27.3 | 67 | 17.4 | 57 | 14.8 | 35 | 9.1 | 154 | 40.1 |
Prolonged hospitalization | 120 | 30 | 25.0 | 20 | 16.7 | 23 | 19.2 | 15 | 12.5 | 48 | 40.0 |
Laboratory-confirmed, medically attended infection with other pathogen* | |||||||||||
None | 72,382 | 4,056 | 5.6 | 3,476 | 4.8 | 3,449 | 4.8 | 3,362 | 4.6 | 9,101 | 12.6 |
Outpatient | 119 | 20 | 16.8 | 7 | 5.9 | 7 | 5.9 | 8 | 6.7 | 30 | 25.2 |
Uncomplicated hospitalization | 64 | 7 | 10.9 | 3 | 4.7 | 5 | 7.8 | 5 | 7.8 | 10 | 15.6 |
Prolonged hospitalization | 37 | 8 | 21.6 | 6 | 16.2 | 5 | 13.5 | 5 | 13.5 | 10 | 27.0 |
Definite, medically attended RSV encounter in the first year of life* | |||||||||||
No | 71,336 | 3,829 | 5.4 | 3,326 | 4.7 | 3,312 | 4.6 | 3,280 | 4.6 | 8,748 | 12.3 |
Yes | 1,266 | 262 | 20.7 | 166 | 13.1 | 154 | 12.2 | 100 | 7.9 | 403 | 31.8 |