Table 2 Instruments used during the baseline visit (PACMAN) and follow-up study visit (PACMAN2)
Baseline visit (PACMAN) | Follow-up (PACMAN2) | |
|---|---|---|
Questionnaires | ||
Questions on general health, allergies, asthma and respiratory symptoms | Questions on general health, allergies, asthma and respiratory symptoms | |
Asthma control (ACQ-6) [19] | Asthma control (ACQ-6) [19] | |
- | Childhood Asthma Control Test (c-ACT), Asthma Control Test (ACT) [20]§ | |
Questions on asthma control in the past 4 seasons [18] | Questions on asthma control in the past 4 seasons [18] | |
Environmental factors (passive smoking, pets, living environment) | Environmental factors (passive smoking, pets, living environment) | |
Active smoking is assessed in children > 12 years of age | ||
Beliefs about Medicines Questionnaire (BMQ) [21] | - | |
Healthcare utilization for respiratory symptoms | Healthcare utilization for respiratory symptoms | |
Exacerbations in the past year (ER visits/OCS usage) | Exacerbations in the past year (ER visits/OCS usage) | |
Demographics | Demographics | |
Current asthma medication use | Current asthma medication use | |
Medication Adherence Rating Scale (MARS) [16] | Medication Adherence Rating Scale (MARS) [16] § | |
- | General RAND questionnaire [22] | |
- | Growth parameters, breast feeding and vaccination status | |
- | Paediatric Asthma Quality of Life Questionnaire (PAQLQ) [23]§ | |
- | Paediatric and Adolescent Rhinoconjunctivitis Quality of Life Questionnaire (PRQLQ and AdolRQLQ) [24, 25]§ | |
- | Allergic Rhinitis and its Impact on Asthma (ARIA) [26]§ | |
- | 6-item Otitis Media Questionnaire (OM-6) [27]§ | |
- | Brouilette Score [28] § | |
- | Food Allergy Quality of Life Questionnaire for children and teenagers (FAQLQ-CF and FAQLQ-TF) [29, 30] § | |
- | Self-Administered Eczema Area and Severity Index (SA-EASI) [31] § | |
- | Children’s Dermatology Life Quality Index (CDLQI) and Infant’s Dermatitis Quality of Life Index Questionnaire [32] § | |
Inhalation technique | ||
Inhalation technique (checklist) | - | |
Medication history | ||
Medication history through pharmacy system | - | |
Lung function | ||
Lung function testing and airway reversibility using hand-held diagnostic spirometer | Lung function testing and airway reversibility in a clinical setting by a trained lung function technician | |
Exhaled breath | ||
Exhaled Nitric Oxide (FeNO) (Niox Mino) | Exhaled Nitric Oxide (FeNO) (Niox Mino) | |
- | Volatile Organic Compounds | |
Saliva | ||
Saliva sample (Oragene) for DNA | Saliva sample (Oragene) for DNA | |
Peripheral blood and plasma | ||
- | Peripheral blood and plasma sample |