Food intake during the previous 24 h as a percentage of usual intake: a marker of hypoxia in infants with bronchiolitis: an observational, prospective, multicenter study

Table 1 Sensitivity, specificity, PPV, NPV, LR ⁺ , LR ^- and odds ratios of clinical signs of hypoxia (SpO2 < 95%) in infants with bronchiolitis

	Sensitivity % [95% IC]	Specificity % [95% IC]	PPV % [95% IC]	NPV % [95% IC]	LR⁺n [95% IC]	LR^-n [95% IC]	Odds ratio n [95% IC]
Suprasternal retraction	50 [21–79]	87 [81–92]	24 [9–45]	96 [91–98]	4 [2–8]	0,6 [0.3 - 1]	6.9 [2.0 - 23.7]
Intercostal retraction	73 [45–92]	80 [73–86]	26 [14–42]	97 [92–99]	3.6 [2–6]	0.3 [0.1 - 78]	10.8 [3.2 - 36.3]
Subcostal retraction	47 [21–73]	72 [64–79]	14 [6–27]	93 [87–97]	1.7 [0.9 - 3]	0.7 [0,5 – 1.2]	2.3 [0.8 - 6.6]
Polypnea (≥ 50/min)	87 [60–98]	62 [53–70]	19 [10–30]	98 [93–100]	2.3 [1.7 - 3]	0.2 [0.06 – 0.8]	10.5 [2.3 - 48.2]
24h FI < 70%	87 [60–98]	65 [56–72]	19 [11–31]	98 [93–100]	2.4 [1.8 – 3.2]	0.2 [0.06 – 0.8]	11.8 [2.6 - 54.2]
24h FI < 60%	67 [38–88]	78 [70–84]	23 [11 \- 38]	96 [91–99]	3 [1.9 – 4.7]	0.4 [0.2 – 0.8]	6.9 [2.2 - 21.7]
24h FI < 50%	60 [32–84]	90 [84–94]	38 [19–59]	96 [91–99]	6.1[3–11]	0.4 [0.2 – 0.8]	13.8 [4.3 - 44.1]
24h FI < 40%	33 [12–62]	96 [92–99]	46 [17–77]	94 [89–97]	8.5 [2.9 - 24]	0.7 [0.5 – 0.99]	12.2 [3.2 - 47.2]

24h FI food intake in previous 24h as a % of usual intake; PPV positive predictive value ; NPV negative predictive value ; LR ⁺ positive likelihood ratio ; LR ^- negative likelihood ratio; [95% CI] 95% confidence interval.

ISSN: 1471-2431