Table 3 Prevalence of chronic developmental health conditions in the NEC and matched control groups between 6–12 and 24–36 months of follow-up

BPD

98 (5%)

19 (14%)

16 (26%)

3 (1.8 – 5.6)**

4 (2–7)**

Malabsorption syndrome†

13 (1%)

2 (1%)

13 (21%)

2.3 (0.5 – 10)

47 (19–116)**

Failure to thrive

132 (6%)

22 (16%)

18 (29%)

3 (1.7 – 5)**

4 (2–6)**

NDD

168 (8%)

21 (15%)

16 (26%)

1.9 (1.2 – 3.2)**

2.4 (1.4 – 4.5)**

Cerebral palsy

17 (1%)

3 (2%)

2 (3%)

2.6 (0.7 – 9)

2.3 (0.5 – 10.8)

GI artificial openings present

42 (2%)

9 (6%)

15 (24%)

3.2 (1.5 – 6.9)**

9 (5–21)**

Metabolic disturbances ^§

58 (3%)

5 (4%)

8 (13%)

1.2 (0.5 – 3)

4.8 (2.1 – 10.7)**

Feeding difficulties

33 (2%)

8 (6%)

14 (23%)

4 (1.7 – 8.4)**

11 (5.2 – 21.8)**

Age: 24–36 Months

Chronic Conditions

Controls

Medical NEC

Surgical NEC

Adjusted odds ratio‡

Adjusted odds ratio‡

(N = 951)

(N= 70)

(N = 35)

(95% CI)

(95% CI)

n (%)

n (%)

n (%)

Medical NEC vs. Controls

Surgical NEC vs. Controls

BPD

14 (1%)

4 (6%)

5 (14%)

4.6 (1.4 – 15)**

5.5 (2–16)**

Malabsorption syndrome†

4 (0.4 %)

0 (0%)

7 (20%)

-

62 (15–249)**

Failure to thrive

97 (10%)

6 (9%)

11 (31%)

0.8 (0.3 – 2)

3 (1.3 - 6)*

NDD

133 (14%)

13 (19%)

13 (37%)

1.5 (0.8 – 2.9)

2.6 (1.2 – 5.6)*

Cerebral palsy

35 (4%)

1 (1%)

4 (11%)

0.4 (0.05 – 3)

2.1 (0.7 – 6.4)

GI artificial openings present

35 (4%)

4 (6%)

10 (29%)

1.8 (0.6 – 5.3)

6 (3–14)**

Metabolic disturbances ^§

29 (3%)

3 (4%)

4 (11%)

1.4 (0.4 – 5)

3.4 (1.1 -10)*

Feeding difficulties

19 (2%)

3 (4%)

4 (11%)

2.4 (0.7 – 9)

4 (1.2 - 13)*