Table 1 Clinical and biochemical characteristics of young adolescents according to IL10 tertiles (n=325, boys=175 and girls=150)
Variables# | T1* | T2* | T3* | P-trend | |||
|---|---|---|---|---|---|---|---|
BMI (kg/m2) | 20.97 | ±4.3 | 20.65± | 4.3 | 19.99 | ±3.2 | 0.0740 |
Body fat (%) | 22.64 | ±8.7 | 21.95± | 7.6 | 20.78 | ±6.78 | 0.0818 |
Waist circumference (cm) | 71.21 | ±11.9 | 70.55± | 10.8 | 69.16 | ±9.9 | 0.1788 |
Fasting glucose (mg/dL) | 90.99 | ±8.67 | 91.81± | 6.07 | 92.25 | ±7.79 | 0.2240 |
Fasting serum insulin (μIU/ml) | 16.95 | ±14.2 | 16.87± | 10.3 | 17.22 | ±15.8 | 0.8848 |
HOMA-IR | 3.98 | ±4.0 | 3.88± | 2.5 | 4.05 | ±4.2 | 0.8940 |
Sytolic BP (mmHg) | 110.89 | ±11.0 | 112.33± | 8.9 | 110.75 | ±8.5 | 0.9094 |
Diastolic BP (mmHg) | 62.88 | ±8.2 | 63.80± | 8.7 | 63.41 | ±7.7 | 0.6371 |
HDL cholesterol (mg/dL) | 54.06 | ±12.3 | 56.31± | 13.4 | 56.59 | ±12.67 | 0.1481 |
LDL- cholesterol (mg/dL) | 89.44 | ±27.0 | 91.64± | 21.2 | 90.73 | ±24.2 | 0.6998 |
Triglyceride ((mg/dL)) | 76.53 | ±35.6 | 70.85± | 31.2 | 78.23 | ±49.6 | 0.7537 |
Total cholesterol (mg/dL) | 159.9 | ±30.2 | 159.63± | 24.2 | 160.75 | ±30.1 | 0.8420 |
Serum iron (ug/dL) | 87 | ±35.8 | 86.52± | 33.1 | 95.32 | ±36.0 | 0.0833 |
Serum TIBC (ug/dL) | 352.1 | ±44.6 | 348.56± | 47.2 | 337.01 | ±37.2 | 0.0114 |
Serum ferritin (ng/ml) | 57.87 | ±36.1 | 55.22± | 37.0 | 55.92 | ±32.0 | 0.6844 |
Transferrin Saturation (%) | 25.17 | ±10.7 | 25.14± | 9.6 | 28.63 | ±11.1 | 0.0167 |
Hepcidin (ng/ml) § | 422.46 | ±418.7 | 554.71± | 446.7 | 698.92 | ±420.7 | <0.0001 |
TNFα (pg/ml) § | 24.56 | ±11.2 | 18.96± | 7.3 | 18.81 | ±6.7 | <0.0001 |
IFNγ (pg/ml) | 6.72 | ±1.7 | 6.34± | 2.3 | 6.24 | ±2.5 | 0.1148 |
NO (uM) § | 9.31 | ±4.3 | 7.10± | 4.2 | 6.69 | ±4.3 | <0.0001 |
IL1β (pg/ml) § | 1.26 | ±0.4 | 1.00± | 0.4 | 0.86 | ±0.2 | <0.0001 |