Skip to main content

Table 4 Reporting of methodological characteristics for different subgroups

From: 10-year trend in quantity and quality of pediatric randomized controlled trials published in mainland China: 2002–2011

Item

Multiple-center

Single-center

p

Teaching hospitals*

Non-teaching

p

Funding

No funding

p

2002-2006

2007-2011

p

 

(n = 25)

(n = 1052)

 

(n = 254)

hospitals* (n = 818)

 

(n = 44)

(n = 1033)

 

(n = 446)

(n = 631)

 

Adequate random

13 (52%)

148 (14.06%)

0.000

46 (18.11%)

114 (13.94%)

0.103

6 (13.64%)

155 (15%)

0.803

12 (2.69%)

149 (23.61%)

0.000

sequence generation

            

(n = 161)

            

Adequate allocation

5 (20%)

5 (0.48%)

0.000

9 (3.54%)

1 (0.12%)

0.000

3 (6.82%)

7 (0.68%)

0.006

1 (0.22%)

9 (1.43%)

0.053

concealment

            

(n = 10)

            

Adequate blinding

2 (8%)

4 (0.38%)

0.007

5 (1.97%)

0 (0%)

0.001

1 (2.27%)

5 (0.48%)

0.222

1 (0.22%)

5 (0.79%)

0.410

(n = 6)

            

Incomplete outcome

12 (48%)

976 (92.78%)

0.000

214 (84.25%)

769 (94.01%)

0.000

29 (65.9%)

959 (92.84%)

0.000

416 (93.27%)

572 (90.65%)

0.123

data (low risk)

            

(n = 988)

            

Selective reporting

0 (0%)

18 (1.71%)

1.000

3 (1.18%)

15 (1.83%)

0.588

0 (0%)

18 (1.74%)

1.000

6 (1.35%)

12 (1.9%)

0.483

(n = 18)

            
  1. *We excluded five studies conducted in scientific research institutions.