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Table 4 Reporting of methodological characteristics for different subgroups

From: 10-year trend in quantity and quality of pediatric randomized controlled trials published in mainland China: 2002–2011

Item Multiple-center Single-center p Teaching hospitals* Non-teaching p Funding No funding p 2002-2006 2007-2011 p
  (n = 25) (n = 1052)   (n = 254) hospitals* (n = 818)   (n = 44) (n = 1033)   (n = 446) (n = 631)  
Adequate random 13 (52%) 148 (14.06%) 0.000 46 (18.11%) 114 (13.94%) 0.103 6 (13.64%) 155 (15%) 0.803 12 (2.69%) 149 (23.61%) 0.000
sequence generation             
(n = 161)             
Adequate allocation 5 (20%) 5 (0.48%) 0.000 9 (3.54%) 1 (0.12%) 0.000 3 (6.82%) 7 (0.68%) 0.006 1 (0.22%) 9 (1.43%) 0.053
concealment             
(n = 10)             
Adequate blinding 2 (8%) 4 (0.38%) 0.007 5 (1.97%) 0 (0%) 0.001 1 (2.27%) 5 (0.48%) 0.222 1 (0.22%) 5 (0.79%) 0.410
(n = 6)             
Incomplete outcome 12 (48%) 976 (92.78%) 0.000 214 (84.25%) 769 (94.01%) 0.000 29 (65.9%) 959 (92.84%) 0.000 416 (93.27%) 572 (90.65%) 0.123
data (low risk)             
(n = 988)             
Selective reporting 0 (0%) 18 (1.71%) 1.000 3 (1.18%) 15 (1.83%) 0.588 0 (0%) 18 (1.74%) 1.000 6 (1.35%) 12 (1.9%) 0.483
(n = 18)             
  1. *We excluded five studies conducted in scientific research institutions.