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Table 3 Associations between prematurity complications and number of CB stem and progenitor cell populations in preterm infants

From: Circulating hematopoietic stem cell count is a valuable predictor of prematurity complications in preterm newborns

Complication

Cord blood cell population

Complication absent [%]

Complication present [%]

p a

  

Mean ± SD (Median)

Mean ± SD (Median)

 

IVH

CD45–lin–CD184+

0.0289 ± 0.0331 (0.0180)

0.0316 ± 0.0276 (0.0200)

0.41

 

CD45+lin–CD184+

0.0020 ± 0.0035 (0.0010)

0.0004 ± 0.0008 (0)

0.014

 

CD133+CD34+

0.342 ± 0.248 (0.306)

0.374 ± 0.258 (0.442)

0.52

 

CD133-CD34+

0.100 ± 0.077 (0.087)

0.152 ± 0.126 (0.086)

0.26

RDS

CD45–lin–CD184+

0.0272 ± 0.0283 (0.0170)

0.0386 ± 0.0433 (0.0215)

0.13

 

CD45+lin–CD184+

0.0020 ± 0.0034 (0.0010)

0.0003 ± 0.0006 (0)

0.0048

 

CD133+CD34+

0.320 ± 0.238 (0.3053)

0.467 ± 0.265 (0.529)

0.027

 

CD133-CD34+

0.095 ± 0.073 (0.083)

0.175 ± 0.128 (0.114)

0.019

BPD

CD45–lin–CD184+

0.0292 ± 0.0321 (0.0180)

0.0328 ± 0.0321 (0.0190)

0.76

 

CD45+lin–CD184+

0.0017 ± 0.0033 (0)

0.0005 ± 0.0008 (0)

0.39

 

CD133+CD34+

0.330 ± 0.244 (0.306)

0.570 ± 0.207 (0.544)

0.013

 

CD133-CD34+

0.101 ± 0.080 (0.086)

0.238 ± 0.132 (0.248)

0.0074

ROP

CD45–lin–CD184+

0.0290 ± 0.0319 (0.0180)

0.0356 ± 0.0341 (0.0188)

0.68

 

CD45+lin–CD184+

0.0017 ± 0.0033 (0)

0.0003 ± 0.0004 (0)

0.20

 

CD133+CD34+

0.344 ± 0.251 (0.310)

0.424 ± 0.220 (0.510)

0.35

 

CD133-CD34+

0.106 ± 0.085 (0.087)

0.186 ± 0.152 (0.162)

0.32

NEC

CD45–lin–CD184+

0.0298 ± 0.0324 (0.0180)

0.0180 ± 0.0046 (0.0190)

0.95

 

CD45+lin–CD184+

0.0017 ± 0.0032 (0)

0 ± 0 (0)

0.12

 

CD133+CD34+

0.338 ± 0.246 (0.310)

0.662 ± 0.014 (0.670)

0.015

 

CD133-CD34+

0.108 ± 0.091 (0.086)

0.214 ± 0.032 (0.211)

0.025

Infection

CD45–lin–CD184+

0.0308 ± 0.0352 (0.0180)

0.0268 ± 0.0244 (0.0190)

0.96

 

CD45+lin–CD184+

0.0020 ± 0.0036 (0.0010)

0.0010 ± 0.0021 (0)

0.034

 

CD133+CD34+

0.345 ± 0.264 (0.307)

0.358 ± 0.220 (0.324)

0.60

 

CD133-CD34+

0.105 ± 0.089 (0.085)

0.123 ± 0.098 (0.092)

0.43

Anemia

CD45–lin–CD184+

0.0298 ± 0.0333 (0.0180)

0.0276 ± 0.0252 (0.0195)

0.95

 

CD45+lin–CD184+

0.0019 ± 0.0034 (0.0010)

0.0005 ± 0.0011 (0)

0.029

 

CD133+CD34+

0.336 ± 0.247 (0.310)

0.409 ± 0.260 (0.464)

0.28

 

CD133-CD34+

0.098 ± 0.077 (0.084)

0.175 ± 0.126 (0.152)

0.031

Any complication

CD45–lin–CD184+

0.0284 ± 0.0298 (0.0180)

0.0308 ± 0.0350 (0.0185)

0.86

 

CD45+lin–CD184+

0.0021 ± 0.0038 (0.0010)

0.0010 ± 0.0019 (0)

0.014

 

CD133+CD34+

0.341 ± 0.250 (0.307)

0.359 ± 0.251 (0.319)

0.71

 

CD133-CD34+

0.099 ± 0.077 (0.085)

0.129 ± 0.107 (0.087)

0.30

  1. a Mann–Whitney test.