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Table 3 Comparing cerebral malaria and uncomplicated malaria

From: Human immunodeficiency virus infection and cerebral malaria in children in Uganda: a case-control study

 

Cerebral Malaria

Uncomplicated Malaria

Unadjusted

 

Variable

n = 100

n = 132

p-value

p-value

 

N (%)

N (%)

OR (95%CI)

adjusted OR (95% CI)

Age (Months)

    

≤59†

81 (81)

90 (68.2)

0.028

0.016

>59

19 (19)

42 (31.8)

1.99 (1.07-3.69)

2.41 (1.14-4.02)‡

Use of mosquito net

54 (54)

86 (65.2)

0.086

0.051

Yes†

46 (46)

46 (34.8)

0.63 (0.37-1.07)

0.58 (0.34-1.01)¶

No

    

Pre-hospital treatment

82 (82)

76 (57.6)

<0.001

0.002

Yes†

18 (18)

56 (42.4)

3.36 (1.81-6.21)

3.02 (1.52-5.99)¶

No

    

Median parasite density/μl

4 (4)

   

>500,000†

96 (96)

1 (0.76)

0.092

0.069

≤500,000

 

131 (99.24)

5.46 (0.53-270.77)

5.23 (0.71-38.59)¶

HIV status

    

Positive†

9 (9)

3 (2.3)

0.022

0.012

Negative

91 (91)

129 (97.7)

4.25 (1.10-16.44)

5.94 (1.23-28.72) ¶

Number of children <5y/household

    

≤3

83 (83)

124 (93.9)

0.008

0.005

>3†

17 (17)

8 (6.1)

3.18 (1.31-7.69)

4.03 (1.51-10.76)¶

  1. CI = confidence interval, OR odds ratio, ‡ adjusted for HIV status, ¶ age-adjusted OR, † reference group, CM = cerebral malaria, UM = uncomplicated malaria