Table 1 Patient characteristics
From: Varicella-zoster virus infections in immunocompromised patients - a single centre 6-years analysis
patient | gender | age [years] | start VZV exanthema until hospital admission | organ involvement | start antiviral therapy | underlying disease/time point of therapy | duration of antiviral therapy | outcome |
|---|---|---|---|---|---|---|---|---|
Oncologic patients | Â | |||||||
1 | m | 4 | 1 day | skin, peripheral blood, bronchial secret, pleural effusion, ascites, myocard, lung, liver, kidneys | immediately, acyclovir i.v. | T-ALL, diagnosis | until death (2nd Day) | death of VZV |
2 | m | 6 | same day | skin | immediately, acyclovir i.v. | c-ALL, maintenance therapy | 7 days | alive, no sequelae |
3 | m | 4 | same day | skin | immediately, acyclovir i.v. | neuroblastoma, maintenance with retinoic acid | 7 days | alive, no sequelae |
4 | m | 5 | same day | skin | immediately, acyclovir | T-ALL, consolidation chemotherapy, herpes zoster | 7 days | alive, no sequelae |
5 | m | 8 | same day | skin | immediately, acyclovir i.v. | T-ALL, induction chemotherapy | 5 days | alive, no sequelae |
6 | f | 1 | same day | skin | immediately, acyclovir i.v. | astrocytoma, induction therapy | 7 days | alive, no sequelae |
7 | m | 7 | same day | skin | immediately, acyclovir i.v. | pro-B-ALL, allogeneic BMT, d +114, herpes zoster | 7 days | DOD |
8 | m | 7 | same day | skin | immediately, acyclovir i.v. | pro-B-ALL, allogeneic BMT, d +60, herpes zoster | 7 days | DOD |
9 | m | 1.8 | 3 days later | skin | immediately, acyclovir i.v. | cALL, diagnosis | 49 days | alive, no sequelae |
Immunocompromised patients | ||||||||
10 | m | 8 | 1 day | skin, liver | immediately, acyclovir and cidofovir | nephrotic syndrome | 7 days | alive, no sequelae |
11 | f | 7 | 1 day | skin | immediately, acyclovir i.v. | juvenile idiopathic arthritis (MTX, prednisone) | 3 days i.v., 5 days p.o. | alive, no sequelae |
12 | f | 5 | same day | skin | immediately, acyclovir i.v. | juvenile idiopathic arthritis (MTX, prednisone) | 3 days* | alive, no sequelae |
13 | f | 4 weeks | 3 days | skin | immediately, acyclovir i.v. | neonatal | 4 days | alive, no sequelae |
14 | m | 3 | same day | skin | immediately, acyclovir i.v. | pemphygoid, enteropathy (prednisone) | 14 days | alive, no sequelae |