Table 3 Primary and secondary outcome in the 4 subgroups of thrombocytopenic neonates.
Mild (100-149 × 109/L) | Moderate (50-99 × 109/L) | Severe (30-49 × 109/L) | Very severe (<30 × 109/l) | P-value | |
|---|---|---|---|---|---|
(N = 122) | (N = 164) | (N = 67) | (N = 69) | ||
Primary Outcome | (N = 117) | (N = 160) | (N = 66) | (N = 68) | |
Number of neonates with IVH≥ grade 2, n (%) | 12 (10) | 22 (14) | 4 (6) | 10 (15) | 0.32 |
IVH, grade 2 | 3 (3) | 7 (4) | 3 (5) | 6 (9) | 0.26 |
IVH, grade 3 | 4 (3) | 6 (4) | 1 (2) | 2 (3) | 0.86 |
PVHI (i.e., IVH grade 4) | 5 (4) | 9 (6) | 0 (0) | 2 (3) | 0.25 |
Secondary Outcome | (N = 122) | (N = 164) | (N = 67) | (N = 69) | |
Number of platelet Txs per transfused patient, median (range), N | 0 (N = 0) | 1 (1-1) (N = 9) | 1 (1-5) (N = 48) | 3 (1-28) (N = 65) | < 0.01 |
Mortality, n (%) | 8 (7) | 17 (10) | 7 (10) | 7 (10) | 0.69 |