Overall | Isolated | Associated | ||||
---|---|---|---|---|---|---|
Variable | Intervention N = 543 | Control N = 372 | Intervention N = 394 | Control N = 305 | Intervention N = 149 | Control N = 67 |
Maternal Age | 26.23 (6.83) | 25.50 (6.67) | 25.88 (6.58) | 25.40 (6.53) | 27.14 (7.39) | 25.92 (7.30) |
Number of prenatal visits | 4.74*** (3.54) | 5.87 (2.91) | 4.47*** (3.56) | 5.95 (2.87) | 5.47 (3.39) | 5.51 (3.09) |
Maternal chronic illness | ||||||
No (%) | 425 (78.7) | 291(82.4) | 315 (80.6) | 237(82.6) | 110 (73.8) | 54(81.8) |
Yes (%) | 115 (21.3) | 62 (17.6) | 76 (19.4) | 50 (17.4) | 39 (26.2) | 12(18.2) |
Ethnic Ancestry | ||||||
Black (%) | 57(10.7) | 31 (8.8) | 41 (10.5) | 26 (9.1) | 16 (11.0) | 5 (7.7) |
Native American (%) | 407 (76.3) | 262(74.4) | 296 (76.1) | 209(72.8) | 111 (76.6) | 53(71.5) |
Other (%) | 70 (13.1) | 59 (16.8) | 52 (13.4) | 52 (18.1) | 18 (12.4) | 7 (10.7) |
Birth weight (grams) | 2,976.7* (648.6) | 3,046.6 (670.3) (797.75) | 3,031.9** (618.1) | 3,123.8 (631.0) | 2,831.0 (704.8) | 2,694.8 (733.5) |
Gestational age (weeks) | 38.75 (2.86) | 38.92 (2.74) | 38.89* (2.80) | 39.19 (2.51) | 38.38 (2.97) | 37.71 (3.37) |
Time of cleft diagnosis | ||||||
Prenatal (%) | 116 (21.6) *** | 38 (10.3) | 64 (16.4)*** | 24 (7.9) | 52 (35.4)** | 14(21.2) |
Other (%) | 421 (78.4) | 332(89.7) | 326 (83.6) | 280(92.1) | 95 (64.6) | 52 (78.8) |
Sex | ||||||
Male (%) | 307 (57.3) | 213(57.3) | 222 (56.4) | 178(58.4) | 85 (57.1) | 35(52.2) |
Female (%) | 236 (43.5) | 159(42.7) | 172 (43.7) | 127(41.6) | 64 (43.0) | 32(47.8) |
Multiple birth | ||||||
No (%) | 529 (97.4) | 361(97.3) | 381(96.7) | 295(97.0) | 148 (99.3) | 66 (98.5) |
Yes (%) | 14 ( 2.6) | 10 (2.7) | 13 (3.3) | 9 (3.0) | 1 (0.7) | 1 (1.5) |
Associated Status | ||||||
Isolated (%) | 394 (72.6) | 305(82.0) | - | - | - | - |
Associated (%) | 149 (27.4) | 67 (18.0) | - | - | - | - |
Type of Cleft | ||||||
Palate only (%) | 142 (26.2) | 92 (24.7) | 83 (21.1) | 66 (21.6) | 59 (39.6) | 26(38.8) |
Lip only (%) | 96 (17.7) | 67 (18.0) | 88 (22.3) | 60 (19.7) | 8 (5.4) | 7 (10.5) |
Lip and Palate (%) | 305 (56.2) | 213(57.3) | 223 (56.6) | 179(58.7) | 82 (55.0) | 34(50.8) |
Type of Delivery | ||||||
Cesarean (%) | 202 (37.2) | 127(34.5) | 132 (33.5) | 94 (31.2) | 70 (47.0) | 33(49.3) |
Other | 341(62.8) | 241(65.5) | 262(66.5) | 207(68.8) | 79 (53.0) | 34(50.8) |