From: Effect of a vitamin/mineral supplement on children and adults with autism
Amino Acids | Neuro-typicals (n = 44) | Arizona Treatment Group (n = 18) | Arizona Placebo Group (n = 20) | ||||||
---|---|---|---|---|---|---|---|---|---|
 |  | Pre | Post | % change | p-value | Pre | Post | % change | p-value |
Histidine | 8.2 +/- 1.3 | 8.7 +/- 2.5 | 9.6 +/- 1.3 | +10% | n.s. | 8.8 +/0 1.5 | 8.0 +/- 1.9 | -9% | n.s. |
Isoleucine | 5.8 +/- 1.6 | 5.3 +/- 1.3 | 5.7 +/- 1.3 | +8% | n.s. | 5.2 +/- 0.8 | 6.0 +/- 1.5 | 16% | 0.03 |
Leucine | 10.7 +/- 2.1 | 11.0 +/- 2.5 | 11.4 +/- 2.8 | +4% | n.s. | 10.5 +/- 2.0 | 10.4 +/- 1.8 | -1% | n.s. |
Lysine | 14.5 +/- 4.8 | 12.6 +/- 3.8 | 14.8 +/- 4.1 | +17% | 0.10 | 14.2 +/- 3.5 | 14.9 +/- 2.8 | +5% | n.s. |
Methionine | 1.75 +/- 0.34 | 1.84 +/- 0.57 | 2.02 +/- 0.48 | +10% | n.s. | 1.92 +/- 0.45 | 1.93 +/- 0.64 | +1% | n.s. |
Phenylalanine | 4.83 +/- 0.83 | 4.61 +/- 0.55 | 4.68 +/- 1.0 | +2% | n.s. | 4.36 +/- 0.63 | 4.65 +/- 0.66 | +7% | n.s. |
Threonine | 8.88 +/- 2.1 | 9.2 +/- 2.6 | 7.9 +/- 1.8 | -14% | 0.07 | 9.4 +/- 3.6 | 8.7 +/- 2.4 | -7% | n.s. |
Tryptophan | 4.33 +/- 1.0 | 3.32 +/- 0.9 | 4.11 +/- 1.7 | +24% | 0.06 | 3.47 +/- 1.1 | 4.17 +/- 1.3 | +20% | 0.04 |
Valine | 20.5 +/- 4.3 | 20.6 +/- 4.3 | 20.0 +/- 4.2 | -3% | n.s. | 18.4 +/- 3.5 | 20.2 +/- 3.7 | +10% | 0.06 |
Alanine | 33.4 +/- 8.9 | 36.6 +/- 9.0 | 37.4 +/- 12 | +2% | n.s. | 36.1 +/- 10 | 36.8 +/- 11 | +2% | n.s. |
Arginine | 6.7 +/- 1.8 | 5.9 +/- 2.2 | 7.5 +/- 1.6 | +26% | 0.006 | 6.9 +/- 2.0 | 7.8 +/- 1.5 | +14% | 0.02 |
Asparagine | 4.38 +/- 0.83 | 4.50 +/- 1.0 | 4.15 +/- 1.0 | -8% | n.s. | 4.26 +/- 1.42 | 3.92 +/- 0.84 | -8% | n.s. |
Aspartate | 0.82 +/- 0.39 | 0.83 +/- 0.37 | 0.88 +/- 0.33 | +6% | n.s. | 0.69 +/- 0.21 | 0.82 +/- 0.37 | +18% | n.s. |
Cystine + cysteine | 3.48 +/- 0.74 | 3.57 +/- 0.72 | 3.36 +/- 1.2 | -6% | n.s. | 3.01 +/- 0.81 | 3.40 +/- 0.87 | +13% | n.s. |
Glutamate | 5.83 +/- 1.8 | 6.9 +/- 1.5 | 7.66 +/- 1.5 | +12% | n.s. | 6.4 +/- 1.5 | 6.6 +/- 1.5 | +4% | n.s. |
Glutamine | 41.3 +/- 6.8 | 43.1 +/- 8.3 | 38.2 +/- 5.9 | -11% | .08 | 42.4 +/- 11 | 38.4 +/- 5.0 | -10% | 0.10 |
Glycine | 27.3 +/- 10 | 23.8 +/- 6.5 | 28.6 +/- 6.7 | +20% | 0.02 | 28.9 +/- 11 | 29.3 +/- 9.1 | +1% | n.s. |
Proline | 15.8 +/- 4.9 | 15.9 +/- 4.2 | 16.0 +/- 4.9 | +1% | n.s. | 15.3 +/- 6.6 | 16.6 +/- 5.7 | +8% | n.s. |
Serine | 9.5 +/- 2.1 | 9.9 +/- 2.1 | 8.9 +/- 1.5 | -10% | 0.01 | 10.6 +/- 2.1 | 9.7 +/- 1.8 | -8% | 0.01 |
Tyrosine | 6.1 +/- 1.6 | 5.5 +/- 1.3 | 5.9 +/- 1.3 | +6% | n.s. | 5.6 +/- 1.1 | 6.0 +/- 1.3 | +8% | n.s. |