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Table 8 Primary Amino Acids.

From: Effect of a vitamin/mineral supplement on children and adults with autism

Amino Acids Neuro-typicals
(n = 44)
Arizona Treatment Group
(n = 18)
Arizona Placebo Group
(n = 20)
   Pre Post % change p-value Pre Post % change p-value
Histidine 8.2
+/- 1.3
8.7
+/- 2.5
9.6
+/- 1.3
+10% n.s. 8.8
+/0 1.5
8.0
+/- 1.9
-9% n.s.
Isoleucine 5.8
+/- 1.6
5.3
+/- 1.3
5.7
+/- 1.3
+8% n.s. 5.2
+/- 0.8
6.0
+/- 1.5
16% 0.03
Leucine 10.7
+/- 2.1
11.0
+/- 2.5
11.4
+/- 2.8
+4% n.s. 10.5
+/- 2.0
10.4
+/- 1.8
-1% n.s.
Lysine 14.5
+/- 4.8
12.6
+/- 3.8
14.8
+/- 4.1
+17% 0.10 14.2
+/- 3.5
14.9
+/- 2.8
+5% n.s.
Methionine 1.75
+/- 0.34
1.84
+/- 0.57
2.02
+/- 0.48
+10% n.s. 1.92
+/- 0.45
1.93
+/- 0.64
+1% n.s.
Phenylalanine 4.83
+/- 0.83
4.61
+/- 0.55
4.68
+/- 1.0
+2% n.s. 4.36
+/- 0.63
4.65
+/- 0.66
+7% n.s.
Threonine 8.88
+/- 2.1
9.2
+/- 2.6
7.9
+/- 1.8
-14% 0.07 9.4
+/- 3.6
8.7
+/- 2.4
-7% n.s.
Tryptophan 4.33
+/- 1.0
3.32
+/- 0.9
4.11
+/- 1.7
+24% 0.06 3.47
+/- 1.1
4.17
+/- 1.3
+20% 0.04
Valine 20.5
+/- 4.3
20.6
+/- 4.3
20.0
+/- 4.2
-3% n.s. 18.4
+/- 3.5
20.2
+/- 3.7
+10% 0.06
Alanine 33.4
+/- 8.9
36.6
+/- 9.0
37.4
+/- 12
+2% n.s. 36.1
+/- 10
36.8
+/- 11
+2% n.s.
Arginine 6.7
+/- 1.8
5.9
+/- 2.2
7.5
+/- 1.6
+26% 0.006 6.9
+/- 2.0
7.8
+/- 1.5
+14% 0.02
Asparagine 4.38
+/- 0.83
4.50
+/- 1.0
4.15
+/- 1.0
-8% n.s. 4.26
+/- 1.42
3.92
+/- 0.84
-8% n.s.
Aspartate 0.82
+/- 0.39
0.83
+/- 0.37
0.88
+/- 0.33
+6% n.s. 0.69
+/- 0.21
0.82
+/- 0.37
+18% n.s.
Cystine + cysteine 3.48
+/- 0.74
3.57
+/- 0.72
3.36
+/- 1.2
-6% n.s. 3.01
+/- 0.81
3.40
+/- 0.87
+13% n.s.
Glutamate 5.83
+/- 1.8
6.9
+/- 1.5
7.66
+/- 1.5
+12% n.s. 6.4
+/- 1.5
6.6
+/- 1.5
+4% n.s.
Glutamine 41.3
+/- 6.8
43.1
+/- 8.3
38.2
+/- 5.9
-11% .08 42.4
+/- 11
38.4
+/- 5.0
-10% 0.10
Glycine 27.3
+/- 10
23.8
+/- 6.5
28.6
+/- 6.7
+20% 0.02 28.9
+/- 11
29.3
+/- 9.1
+1% n.s.
Proline 15.8
+/- 4.9
15.9
+/- 4.2
16.0
+/- 4.9
+1% n.s. 15.3
+/- 6.6
16.6
+/- 5.7
+8% n.s.
Serine 9.5
+/- 2.1
9.9
+/- 2.1
8.9
+/- 1.5
-10% 0.01 10.6
+/- 2.1
9.7
+/- 1.8
-8% 0.01
Tyrosine 6.1
+/- 1.6
5.5
+/- 1.3
5.9
+/- 1.3
+6% n.s. 5.6
+/- 1.1
6.0
+/- 1.3
+8% n.s.
  1. The average levels of primary amino acids in plasma (in units of micromoles per 100 ml) measured in the Neurotypical group and the Autism Treatment and Autism Placebo groups (pre and post) who completed the study are reported below, along with their standard deviations. The p-value for a t-test comparison of the change in the level is reported. If the p-value is below 0.05, then the result is highlighted.