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Table 5 Minerals: The average levels of minerals measured in the Neurotypical group and the Arizona Autism Treatment and Arizona Autism Placebo groups (pre and post) who completed the study are reported below, along with their standard deviations.

From: Effect of a vitamin/mineral supplement on children and adults with autism

Essential Minerals + other minerals

Neuro-typicals

(n = 44)

Treatment Group

(n = 19)

Placebo Group

(n = 20)

  

Pre

Post

% change

p-value

Pre

Post

% change

p-value

Calcium-WB

(mg/dL)

5.8

+/- 0.3

5.9

+/- 0.4

6.0

+/0.4

+1%

n.s.

5.8

+/- 0.3

5.6

+/- 0.5

-2%

n.s.

Calcium-RBC

(ug/g)

22.4

+/- 6

19.2

+/- 7.9

27.4

+/- 3.6

+43%

0.001

19.5

+/- 7.5

25.2

+/- 4.3

+30%

0.02

Calcium-Serum

(mg/dL)

9.60

+/- 0.2

9.65

+/- 0.4

9.51

+/- 0.3

-1%

0.07

9.59

+/- 0.4

9.53

+/- 0.3

0%

n.s.

Chromium-RBC

(ng/g)

0.80

+/- 0.4

1.02

+/- 0.50

0.81

+/- 0.6

-21%

n.s.

0.77

+/- 0.44

0.70

+/- 0.3

-9%

n.s.

Copper-WB

(ug/dL)

89

+/- 14

91.2

+/- 13

95.9

+/- 17

+5%

0.09

93.9

+/- 10

95.5

+/- 13

+2%

n.s.

Copper-RBC

(ug/g)

0.72

+/- 0.09

0.75

+/- 0.08

0.78

+/- 0.08

+4%

0.06

0.74

+/- 0.08

0.77

+/- 0.08

+4%

n.s.

Iodine-Urine

(ug/mg creatinine)

0.26

+/- 0.2

0.28

+/- 0.26

0.43

+/- 0.27

+54%

0.03*

0.23

+/- 0.15

0.22

+/- 0.15

-5%

n.s.

Iron-RBC

(ug/g)

833

+/- 64

887

+/- 101

806

+/- 54

-9%

0.006

883

+/- 80

826

+/- 51

-7%

0.02

Iron-Serum

(ug/dL)

87

+/- 35

91

+/- 34

88

+/- 46

-3%

n.s.

80

+/- 33

81

+/- 25

+2%

n.s.

   Serum Ferritin

36.9

+/- 17

42.1

+/- 23

37.3

+/- 23

-11%

n.s.

41.3

+/- 25.1

33.4

+/- 22

-19%

0.004

Lithium-WB

(ug/L)

3.6

+/- 6

1.82

+/- 0.8

10.6

+/-5.1

+485%

.000001

1.60

+/- 0.7

1.47

+/- 0.7

-8%

n.s.

Magnesium-WB

(mg/dL)

3.64

+/- 0.26

3.44

+/- 0.19

3.62

+/- 0.25

+5%

0.00007

3.65

+/- 0.41

3.81

+/-0.42

+4%

0.03

Magnesium-RBC (ug/g)

47.5

+/- 5

48.6

+/- 7.5

44.9

+/- 4.0

-8%

0.03

49.4

+/- 5.8

47.9

+/- 6.0

-3%

n.s.

Magnesium-Serum

(mg/dL)

2.03

+/- 0.15

1.90

+/- 0.13

1.95

+/- 0.15

+2%

n.s.

1.93

+/- 0.14

1.97

+/- 0.15

+2%

n.s.

Manganese-WB

(ug/L)

11.6

+/- 3

11.0

+/- 3.3

13.6

+/- 4.4

+23%

0.0006

12.0

+/- 4.7

14.5

+/- 5.0

+21%

0.00002

Manganese-RBC (ug/g)

0.018

+/- 0.005

0.019

+/- 0.007

0.019

+/- 0.006

+1%

n.s.

0.020

+/- 0.006

0.019

+/- 0.007

-4%

n.s.

Molybdenum-WB (ug/L)

1.39

+/- 0.3

1.27

+/- 0.23

1.88

+/- 0.9

+48%

0.007*

1.34

+/- 0.3

1.37

+/- 0.3

+3%

n.s.

Molybdenum-RBC (ng/g)

0.98 +/- 0.2

1.01

+/- 0.3

1.32

+/- 0.0007

+31%

0.06*

0.87

+/- 0.26

0.93

+/- 0.2

+7%

n.s.

Phosphorus-RBC (ug/g)

567

+/- 43

587

+/- 73

546

+/- 39

-7%

0.01

598

+/- 48

564

+/-37

-6%

0.002

Phosphorus-Serum

(mg/dL)

4.58

+/- 0.5

4.52

+/- 0.5

4.47

+/- 0.6

-1%

n.s.

4.57

+/- 0.5

4.68

+/- 0.7

+2%

n.s.

Potassium -RBC-mEq/L

76.9

+/- 4.1

78.1

+/- 6.2

75.5

+/- 4.4

-3%

n.s.

81.1

+/- 5.1

77.2

+/- 5.1

-5%

0.01

Potassium-Serum

mEq/L

4.17

+/- 0.3

4.12

+/- 0.3

4.21

+/- 0.3

+2%

n.s.

4.01

+/- 0.3

4.04

+/- 0.3

1%

n.s.

Selenium-WB

(ug/L)

210

+/- 20

209

+/- 25

223

+/- 28

+7%

0.001

211

+/- 39

218

+/- 44

+3%

0.05

Selenium-RBC

(ug/g)

0.23

+/- 0.03

0.251

+/- 0.025

0.235

+/- 0.03

-6%

0.007

0.244

+/- 0.052

0.221

+/- 0.04

-10%

0.002

Sodium-Serum

mEq/L

137

+/- 1

137

+/- 2

137

+/- 1

0%

n.s.

138

+/- 3

138

+/- 2

0%

n.s.

Vanadium-RBC

(ng/g)

0. 22 +/- 0.07

0. 22

+/- 0.09

0. 21

+/- 0.05

-5%

n.s.

0.21

+/- 0.04

0.23

+/- 0.09

+10%

n.s.

Zinc-WB

(ug/dL)

555

+/- 74

546

+/- 70

556

+/- 68

+2%

n.s.

559

+/- 59

567

+/-59

+1%

n.s.

Zinc-RBC

(ug/g)

8.9

+/- 1.4

9.1

+/- 1.5

8.6

+/- 1.2

-5%

n.s.

9.1

+/- 1.1

8.8 +/- 1.2

-3%

n.s.

Non-essential minerals

         

Boron-RBC

(ug/g)

0.025

+/- 0.007

0.031

+/- 0.015

0.022

+/- 0.008

-30%

0.004

0.025

+/- 0.013

0.019 +/- 0.010

-24%

n.s.

Strontium-WB

(ug/L)

24

+/- 6

21.6

+/- 3.7

22.8

+/-4.5

+6%

n.s.

29.1

+/- 10

28.6

+/-10

-2%

n.s.

  1. Biomarker data was obtained only for the Arizona autism group. The p-value for a t-test comparison of the change in the level is reported. If the p-value is below 0.05, then the result is highlighted.
  2. * The ttest for urinary iodine and WB & RBC Molybdenum was done after a square root transformation of the data, since the initial data was not close to a Gaussian distribution.