Use of rifampin in persistent coagulase negative staphylococcal bacteremia in neonates

BMC Pediatrics

Table 1 Baseline characteristics of all included patients.

	Non-persistent CoNS bacteremia N = 120	Persistent CoNS bacteremia N = 17	P-value
Prenatal Steroids			0.668
0 doses	50 (43.1%)	9(52.9%)
1 dose	47 (40.5%)	5 (29.4%)
2 doses	19 (16.4%)	3 (17.6%)
Chorioamnionitis*	9 (7.8%)	1 (5.9%)	0.784
PROM**	14 (12.0%)	2 (11.8%)	0.981
Asphyxia***	7 (5.8%)	0 (0%)	0.307
Gestational age, weeks	29.4 ± 3.3	28.0 ± 2.3	0.093
Birth weight, g	1,327 ± 686	874 ± 204	0.008
Gender (male)	71 (59.2%)	10 (58.8%)	0.979
			Multivariate P-value (corrected for birth weight)
Hyperglycemia****	8 (6.7%)	8 (47.1%)	0.007
IVH grade 3/4	9 (7.5%)	0 (0.0%)	0.999
Cystic PVL	2 (1.7%)	1 (5.9%)	0.640
NEC grade 2/3	4 (3.3%)	2 (11.8%)	0.766
RDS grade 3/4	23 (19.2%)	7 (41.2%)	0.788
BPD*****	26 (21.7%)	9 (52.9%)	0.771
Postnatal steroids	7 (5.8%)	4 (23.5%)	0.652
Died during admission	3 (2.5%)	1 (5.9%)	0.754

* Smelly amniotic fluid, maternal fever or signs of infection at birth
** Rupture of membranes >24 hours
*** Presence of minimal 3 criteria:
1) Decelerative CTG or meconium containing amniotic fluid
2) Umbilical cord pH <7.10
3) Apgar score <5 after 5 minutes
4) Spontaneous respiratory depression >5 minutes after birth
5) Multiple organ failure
**** Glucose levels of >10 mmol/L during >12 hours, treated with insulin >12 hours
***** Need for oxygen-therapy at a gestational age of 36 weeks or at discharge

ISSN: 1471-2431